X29A Publications


Calendar Year
Total Pubs
Premier Pubs *
2009
78
30
2008
93
30
2007
87
41
2006
50
24
2005
19
9
2004
2
2


  1. A Orville, G Lountos, S Finnegan, G Gadda, R Prabhakar, Crystallographic, Spectroscopic, and Computational Analysis of a Flavin C4a-Oxygen Adduct in Choline Oxidase, Biochemistry, 48, 720–728 (2009).
  2. L Clark, P Boriack-Sjodin, E Day, J Eldredge, C Fitch, M Jarpe, S Miller, Y Li, K Simon, H van Vlijmen, An Antibody Loop Replacement Design Feasibility Study and a Loop-Swapped Dimer Structure, Protein Eng. Des. Sel., 22(2), 93-101 (2009).
  3. T Brandao, H Robinson, S Johnson, A Hengge, Impaired Acid Catalysis by Mutation of a Protein Loop Hinge Residue in a YopH Mutant Revealed by Crystal Structures, J. Am. Chem. Soc., 131(2), 778–786 (2009).[ premier ]
  4. H Lim, C Miller, Intracellular Proton-Transfer Mutants in a CLC Cl–/H+ Exchanger, J Gen. Physiol., 133, 131-138 (2009).
  5. O Ezezika, N Younger, J Lu, D Kaiser, Z Corbin, B Nolen, D Kovar, T Pollard, Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: Insights from Crystal Structures of Fission Yeast Proflin, J. Biol. Chem., 284(4), 2088-2097 (2009).
  6. Y Tan, S Chan, T Ong, L Yit, Y Tiong, F Chew, J Sivaraman, Y Mok, Structures of Two Major Allergens, Bla g 4 and Per a 4, From Cockroaches and Their IgE Binding Epitopes, J. Biol. Chem., 284, 3148-3157 (2009).
  7. J Lafrance-Vanasse, M Lefebvre, P Di Lello, J Sygusch, J Omichinski, Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-Bound Forms, J. Biol. Chem., 284, 938-944 (2009).
  8. P Pattanaik, C Bethel, A Hujer, K Hujer, A Distler, M Taracila, V Anderson, T Fritsche, R Jones, Strategic Design of an Effective beta-Lactamase Inhibitor, J. Biol. Chem., 284, 945-953 (2009).
  9. Y Li, C Cao, W Jia, L Yu, M Mo, Q Wang, Y Huang, J Lim, M Ishihara, Structure of the F-Spondin Domain of Mindin, an Integrin Ligand and Pattern Recognition Molecule, EMBO J., 28(3), 286-297 (2009).[ premier ]
  10. F Scott, B Stec, C Pop, M Dobaczewska, J Lee, E Monosov, H Robinson, G Salvesen, R Schwarzenbacher, S Riedl, The Fas-FADD Death Domain Complex Structure Unravels Signalling by Receptor Clustering, Nature, 457, 1019-1022 (2009).[ premier ]
  11. A Tripathi, Y Ren, P Jeffrey, F Hughson, Structural Characterization of Tip20p and Dsl1p, Subunits of the Dsl1p Vesicle Tethering Complex, Nat. Struct. Mol. Biol., 16(2), 114 (2009).[ premier ]
  12. J Woo, J Lim, H Shin, M Suh, B Ku, H Lee, K Joo, H Robinson, J Lee, Structural Studies of a Bacterial Condensin Complex Reveal ATP-Dependent Disruption of Intersubunit Interactions, Cell, 136, 85–96 (2009).[ premier ]
  13. J Liu, D Bolstad, A Smith, N Priestley, D Wright, A Anderson, Probing the Active Site of Candida Glabrata Dihydrofolate Reductase with High Resolution Crystal Structures and the Synthesis of New Inhibitors, Chem. Biol. Drug Des., 73, 62-74 (2009).
  14. C Quezada, S Hicks, J Galan, C Stebbins, A Family of Salmonella Virulence Factors Functions as a Distinct Class of Autoregulated E3 Ubiquitin Ligases, Proc Natl Acad Sci USA, 106, 4864-4869 (2009).[ premier ]
  15. G Buchko, H Robinson, A Addlagatta, Structural Characterization of the Protein cce_0567 from Cyanothece 51142, a Metalloprotein Associated with Nitrogen Fixation in the DUF683 Family, Biochim Biophys Acta, 1794(4), 627-633 (2009).
  16. A Serganov, L Huang, D Patel, Coenzyme Recognition and Gene Regulation by a Flavin Mononucleotide Riboswitch, Nature, 458, 233-237 (2009).[ premier ]
  17. D Gallagher, N Smith, S Kim, H Robinson, P Reddy, Profound Asymmetry in the Structure of the cAMP-free cAMP Receptor Protein (CRP) from Mycobacterium tuberculosis, J. Biol. Chem., 284, 8228–8232 (2009).
  18. J Gutierrez, T Crowder, A Rinaldo-Matthis, M Ho, S Almo, V Schramm, Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing., Nat. Chem. Biol., 5(4), 251-257 (2009).[ premier ]
  19. Q Han, H Robinson, T Cai, D Tagle, J Li, Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III, Mol. Cell. Bio., 29(3), 784-793 (2009).[ premier ]
  20. V Nayak, M Dessau, K Kucera, K Anthony, M Ledizet, Y Modis, Crystal Structure of Dengue Type 1 Envelope Protein in the Postfusion Conformation and its Implication for Receptor Binding, Membrane Fusion and Antibody Recognition, J. Virology, 83, 4338 (2009).
  21. M Ho, J Menetret, H Tsuruta, K Allen, The Origin of the electrostatic Perturbation in Acetoacetate Decarboxylase, Nature, 459, 393 (2009).[ premier ]
  22. D Xiang, C Xu, D Kumaran, A Brown, M Sauder, S Burley, S Swaminathan, F Raushel, Functional Annotation of Two New Carboxypeptidases from the Amidohydrolase Superfamily of Enzymes, Biochemistry, 48, 4567-4576 (2009).
  23. A Heroux, D Bozinovski, M Valley, P Fitzpatrick, A Orville, Crystal Structures of Intermediates in the Nitroalkane Oxidase Reaction, Biochemistry, 48, 3407-3416 (2009).
  24. Y Zhang, R Cao, F Yin, M Hudock, R Guo, Y Song, J No, K Bergan, A Leon, Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR Investigation, J. Am. Chem. Soc., 131, 5153-5162 (2009).[ premier ]
  25. Q Han, H Robinson, T Cai, D Tagle, J Li, Structural Insight into the Inhibition of Human Kynurenine Aminotransferase I/Glutamine Transaminase K, J. Med. Chem., 52, 2786-2793 (2009).
  26. J Cochrane, S Lipchock, K Smith, S Strobel, Structural and Chemical Basis for Glucosamine 6-Phosphate Binding and Activation of the glmS Ribozyme, Biochemistry, 48(15), 3239-3246 (2009).
  27. D Xiang, Y Patskovsky, C Xu, A Meyer, J Sauder, S Burley, S Almo, F Raushel, Functional Identification of Incorrectly Annotated Prolidases from the Amidohydrolase Superfamily of Enzymes, Biochemistry, 48(17), 3730–3742 (2009).
  28. Z Zhou, J Zhen, N Karpowich, C Law, M Reith, D Wang, Antidepressant Specificity of Serotonin Transporter Suggested by Three LeuT-SSRI Structures, Nat. Struct. Mol. Biol., 16, 652-657 (2009).[ premier ]
  29. K Frey, J Liu, M Lombardo, D Bolstad, D Wright, A Anderson, Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternative Conformation of NADPH that may be Linked to Trimethoprim Resistance, J. Mol. Biol., 387, 1298-1308 (2009).
  30. J Drumm, K Mi, P Bilder, M Sun, J Lim, H Bielefeldt-Ohmann, R Basaraba, M So, G Zhu, Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP Binding: Requirement for Establishing Chronic Persistent Infection, Plos Pathog., 5(5), 460 (2009).
  31. T Garrett, A Burgess, H Gan, R Luwor, G Cartwright, F Walker, S Orchard, A Clayton, E Nice, Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR, Proc Natl Acad Sci USA, 106, 5082-5087 (2009).[ premier ]
  32. U Pieper, R Chiang, J Seffernick, S Brown, M Glasner, L Kelly, N Eswar, M Sauder, J Bonanno, Target Selection and Annotation for the Structural Genomics of the Amidohydrolase and Enolase Superfamilies, J. Struct. Funct. Genomics, 10(2), 107-125 (2009).
  33. Q Han, T Cai, D Tagle, H Robinson, J Li, Substrate Specificity and Structure of Human aminoadipate aminotransferase/kynurenine aminotransferase II, Bioscience Rep., 28(4), 205-215 (2009).
  34. C Jobichen, A Fernandis, A Velazquez-Campoy, K Leung, Y Mok, M Wenk, J Sivaraman, Identification and Characterization of the Lipid-Binding Property of GrlR, a Locus of Enterocyte Effacement Regulator, Biochem. J., 420(2), 191-199 (2009).
  35. S Tulsidas, S Thangamani, B Ho, J Sivaraman, J Ding, Crystallization of a Nonclassical Kazal-type Carcinoscorpius Rotundicauda Serine Protease Inhibitor, CrSPI-1, Complexed with Subtilisin, Acta Cryst. F, 65(Pt 5), 533-535 (2009).
  36. T Schalch, G Job, V Noffsinger, S Shanker, C Kuscu, L Joshua-Tor, J Partridge, High Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3 is Required to Establish Centromeric Hterochromatin, Mol. Cell, 34, 36-46 (2009).[ premier ]
  37. E Hearn, D Patel, D Lepore, M Indic, B van den Berg, Transmembrane Passage of Hydrophobic Compounds Through a Protein Channel Wall, Nature, 458, 367-370 (2009).[ premier ]
  38. S Li, X Tang, J Seetharaman, C Yang, Y Gu, J Zhang, H Du, J Shih, C Hew, Diminerization of Hepatitis E Virus Capsid Protein E2s Domain is Essential for Virus-Host Interaction, Plos Pathog., 5(8), 1-10 (2009).
  39. Y Fang, H Jayaram, T Shane, L Partensky, F Wu, C williams, Y Xiong, C Miller, Structure of a Prokaryotic Virtual Proton Pump at 3.2 Ε Resolution, Nature, 460, 1040-1043 (2009).[ premier ]
  40. G Gurel, G Blaha, P Moore, U2504 Determines the Species Specificity of the A-site Cleft Antibiotics: The sStructures of Tiamulin, Homoharringtonine and Bruceantin Bound to the Ribosome, J. Mol. Biol., 389, 146-156 (2009).
  41. L Matthews, A Duong, A Prasad, B Duncker, A Guarne, Crystallization and Preliminary X-ray Diffraction Analysis of motif N from Saccharomyces cerevisiae Dbf4, Acta Cryst. F, 65(9), 890-894 (2009).
  42. Y Chung, T Brendler, S Austin, A Guarne, Structural Insights into the Cooperative Binding of SeqA to a Tandem GATC Repeat, Nucleic Acids Res., 37(10), 3143-52 (2009).[ premier ]
  43. H Zhao, A Heroux, R Sequeira, L Tang, Preliminary Crystallographic Studies of the Regulatory Domain of Response Regulator YycF from an Essential Two-Component Signal Transduction System, Acta Cryst. F, F65, 719-722 (2009).
  44. J Lulo, S Yuzawa, J Schlessinger, Crystal Structures of Free and Ligand-Bound Focal Adhesion Targeting Domain of Pyk2, Biochem. Biophys. Res. Commun., 383(3), 347-352 (2009).
  45. G Blaha, R Stanley, T Steitz, Formation of the First Peptid Bond: the Structure of EF-P Bound to the 70S Ribosome, Science, 325, 966 (2009).[ premier ]
  46. A Bera, V Atanasova, H Robinson, E Eisenstein, J Coleman, E Pesci, J Parsons, Structure of PqsD, a Pseudomonas Quinolone Signal Biosynthetic Enzyme, in Complex with Anthranilate, Biochemistry, 48(36), 8644-55 (2009).
  47. B Ibrahim, N Kanneganti, G Rieckhof, A Das, D Laurents, J Palenchar, V Bellofatto, D Wah, Structure of the C-terminal Domain of Transcription Facto IIB from Trypanosoma brucei, Proc Natl Acad Sci USA, 106, 13242-7 (2009).[ premier ]
  48. S Bowley, N Okumura, S Lord, Impaired Protofibril Formation in Fibrinogen γN308K Is Due to Altered D:D and “A:a” Interactions, Biochemistry, 48, 8656–8663 (2009).
  49. C Zhan, Q Yan, Y Patskovsky, Z Li, R Toro, A Meyer, H Cheng, M Brenowitz, S Nathenson, S Almo, Biochemical and Structural Characterization of the Human TL1A Ectodomain, Biochemistry, 48, 7636–7645 (2009).
  50. H Li, Structural and Biochemical Studies of TIGAR and ZnuA, Ph.D. Thesis. Brown University, Providence (2009).
  51. S Xiang, A Cooper-Morgan, X Jiao, M Kiledjian, J Manley, L Tong, Structure and Function of the 5'->3' Exoribonuclease Rat1 and its Activating Partner Rai1, Nature, 458, 784-788 (2009).[ premier ]
  52. G Clayton, S Aller, J Wang, V Unger, J Morais-Cabral, Combining Electron Crystallography and X-ray Crystallography to Study the MlotiK1 Cyclic Nucleotide-Regulated Potassium Channel, J. Struct. Biol., 167(3), 220-226 (2009).
  53. F Zhang, M Hu, G Tian, P Zhang, D Finley, P Jeffrey, Y Shi, Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii, Mol. Cell, 34(4), 473-484 (2009).[ premier ]
  54. C Chou, L Yu, L Tong, Crystal Structure of Biotin Carboxylase in Complex with Substrates and Implications for Its Catalytic Mechanism, J. Biol. Chem., 284, 11690-11697 (2009).
  55. M Navarro, N De, N Bae, Q Wang, H Sondermann, Structural Analysis of the GGDEF-EAL Domain-Containing c-di-GMP Receptor FimX, Structure, 17(8), 1104-1116 (2009).
  56. G Yang, A Bolotnikov, Y Cui, G Camarda, A Hossain, R James, Impurity Gettering Effect of Te Inclusions in Cdznte Single Crystals, J. Cryst. Growth, 311(1), 99-102 (2009).
  57. G Lin, D Li, L Sorio de Carvalho, H Deng, H Tao, G Vogt, K Wu, J Schneider, T Chidawanyika, Inhibitors Selective for Mycobacterial Versus Human Proteasomes, Nature, 461, 621-627 (2009).[ premier ]
  58. M Swan, R Johnson, L Prakash, S Prakash, A Aggarwal, Structural Basis of High-Fidelity DNA Synthesis by Yeast DNA Polymerase δ, Nat. Struct. Mol. Biol., 16, 979-986 (2009).[ premier ]
  59. B Nolen, N Tomasevic, A Russell, D Pierce, Z Jia, C McCormick, J Hartman, R Sakowicz, T Pollard, Characterization of Two Classes of Small Molecule Inhibitors of Arp2/3 Complex, Nature, 460, 1031-1034 (2009).[ premier ]
  60. J Alvarado, A Nemkal, J Sauder, M Russell, D Akiyoshi, W Shi, S Almo, L Weiss, Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470, 168, 158–167 (2009).
  61. M Mitchell, H Nam, A Carter, A McCall, C Rence, A Bennett, B Gurda, R McKenna, M Porter, Production, Purification and Preliminary X-ray Crystallographic Studies of Adeno-Associated Virus Serotype 9, Acta Cryst. F, 65, 715–718 (2009).
  62. K Chattopadhyay, U Ramagopal, S Nathenson, S Almo, 1.8 Ε Structure of Murine GITR Ligand Dimer Expressed in Drosophila Melanogaster S2 Cells, Acta Cryst. D, 65(5), 434-439 (2009).
  63. A Cheng, J Speir, Y Yuan, J Johnson, S Wong, Preliminary X-ray Data Analysis of Crystalline Hibiscus Chlorotic Ringspot Virus, Acta Cryst. F, 65(6), 589-593 (2009).
  64. T Castano, H Wang, N Campillo, S Ballester, C Gonzalez-Garcia, J Hernandez, C Perez, J Cuenca, A Perez-Castillo, Synthesis, Structural Analysis, and Biological Evaluation of Thioxoquinazoline Derivatives as Phosphodiesterase 7 Inhibitors, ChemMedChem, 4, 866-876 (2009).
  65. K Sippel, S Boehlein, Y Sakai, J Quirit, M Agbandje-McKenna, C Rosser, R McKenna, Cloning, Expression, Purification, Crystallization and Preliminary X-ray Analysis of Mycoplasma Genitalium Protein MG289, Acta Cryst. F, 65, 910-912 (2009).
  66. T Wang, H Li, G Lin, C Tang, D Li, C Nathan, K Heran Darwin, Structural Insights on the Mycobacterium tuberculosis Proteasomal ATPase Mpa, Structure, 17, 1377–1385 (2009).
  67. P Kiser, M Golczak, D Lodowski, M Chance, K Palczewski, Crystal Structure of Native RPE65, the Retinoid Isomerase of the Visual Cycle, Proc Natl Acad Sci USA, 106, 17325–17330 (2009).[ premier ]
  68. G Buchko, Pentapeptide Repeat Proteins and Cyanobacteria, Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications, p. 233-257, Nova Science Publishers, Inc., New York (2009).
  69. E Burgos, M Ho, S Almo, V Schramm, A Phosphoenzyme Mimic, Overlapping Catalytic Sites and Reaction Coordinate Motion for Human NAMPT, Proc Natl Acad Sci USA, 106(33), 13748–13753 (2009).[ premier ]
  70. H Seo, Y Ma, E Debler, D Wacker, S Kutik, G Blobel, A Hoelz, Structural and Functional Analysis of Nup120 Suggests Ring Formation of the Nup84 Complex, Proc Natl Acad Sci USA, 106, 14281-14286 (2009).[ premier ]
  71. U Samanta, C Wilder, B Bahnson, Crystallization and Preliminary X-Ray Crystallographic Analysis of Human Plasma Platelet Activating Factor Acetylhydrolase, Protein Peptide Lett., 16(1), 97-100 (2009).
  72. R Agarwal, J Schmidt, R Stafford, S Swaminathan, Mode of VAMP Substrate Recognition and Inhibition of Clostridium botulinum Neurotoxin F, Nat. Struct. Mol. Biol., 16(7), 789-794 (2009).[ premier ]
  73. J Jordan, J Arndt, K Hanf, G Li, J Hall, S Demarest, F Huang, X Wu, B Miller, Structural Understanding of Stabilization Patterns in Engineered Bispecific lg-like Antibody Molecules, Proteins: Struc. Func. Genet., 77(4), 832-841 (2009).
  74. Q Wang, M Navarro, G Peng, E Molinelli, G Lin, B Judson, K Rajashankar, H Sondermann, Molecular Mechanism of Membrane Constriction and Tubulation Mediated by the F-BAR Protein Pacsin/Syndapin, Proc Natl Acad Sci USA, 106(31), 12700-12705 (2009).[ premier ]
  75. M Swan, R Johnson, L Prakash, S Prakash, A Aggarwal, Structure of the Human Rev1–DNA–dNTP Ternary Complex, J. Mol. Biol., 390, 699–709 (2009).
  76. D Gallagher, N Smith, S Kim, H Robinson, P Reddy, Protein Crystal Engineering of YpAC-IV Using a Strategy of Excess Charge Reduction, Cryst. Growth Des., 9(8), 3570–3574 (2009).
  77. M Ho, M Cassera, D Madrid, L Ting, P Tyler, K Kim, S Almo, V Schramm, Structural and Metabolic Specificity of Methylthiocoformycin for Malarial Adenosine Deaminases, Biochemistry, 48, 9618–9626 (2009).
  78. A Gelinas, M Paschini, F Reyes, A Heroux, R Batey, V Lundblad, D Wuttke, F Reyes, F Reyes, F Reyes, Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain, Proc Natl Acad Sci USA, 106(46), 19298-19303 (2009).[ premier ]
  79. S Zheng, G Kaur, H Wang, M Li, M MacNaughtan, X Yang, S Reid, J Prestegard, B Wang, Design, Synthesis, and Structure-Activity Relationship, Molecular Modeling, and NMR Studies of a Series of a Phenyl Alkyl Ketones as Highly Potent and Selective Phosphodiesterase-4 Inhibitors, J. Med. Chem., 51(24), 7673-7688 (2008).
  80. X Zhou, Q Sun, R Kini, J Sivaraman, A Universal Method for Fishing Target Proteins from Mixtures of Biomolecules using Isothermal Titration Calorimetry, Protein Sci., 17(10), 1798-1804 (2008).
  81. Y Tan, H Yu, K Leung, J Sivaraman, Y Mok, Structure of AscE and Induced Burial Regions in AscE and AscG upon Formation of the Chaperone Needle-subunit Complex of Type III Secretion System in Aeromonas Hydrophila, Protein Sci., 17(10), 1748-1760 (2008).
  82. X Hu, H Wang, H Ke, B Kuhlman, Computer-Based Redesign of a Beta Sandwich Protein Suggests That Extensive Negative Design is not Required for de novo beta Sheet Design, Structure, 16(12), 1799-805 (2008).
  83. S Ragumani, D Kumaran, S Burley, S Swaminathan, Crystal Structure of a Putative Lysostaphin Peptidase from Vibrio cholerae, Proteins: Struc. Func. Bioinformatics, 72(3), 1096-1103 (2008).
  84. S Sunita, K Tkaczuk, E Purta, J Kasprzak, S Douthwaite, J Bujnicki, J Sivaraman, Crystal Structure of the Escherichia coli 23S rRNA: m{5}C Methyltransferase RlmI (YccW) Reveals Evolutionary Links Between RNA Modification Enzymes, J. Mol. Biol., 383(3), 652-666 (2008).
  85. X Zhou, T Tan, S Valiyaveettil, M Go, R Kini, A Velazquez-Campoy, J Sivaraman, Structural Characterization of Myotoxic Ecarpholin S From Echis carinatus Venom, Biophys. J., 95, 3366–3380 (2008).
  86. Y Xu, Y Chen, P Zhang, P Jeffrey, Y Shi, Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation, Mol. Cell, 31, 873–885 (2008).[ premier ]
  87. Y Hsu, G Jubelin, F Taieb, J Nougayrθde, E Oswald, C Stebbins, Structure of the Cyclomodulin Cif from Pathogenic Escherichia coli, J. Mol. Biol., 384(2), 465-477 (2008).
  88. E Debler, Y Ma, H Seo, K Hsia, T Noriega, G Blobel, A Hoelz, A Fence-like Coat for the Nuclear Pore Membrane, Mol. Cell, 32, 815–826 (2008).[ premier ]
  89. S Singh, C Piscitelli, A Yamashita, E Gouaux, A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation, Science, 322, 1655-1661 (2008).[ premier ]
  90. D Kumaran, R Rawat, A Ahmed, S Swaminathan, Substrate Binding Mode and its Implication on Drug Design for Botulinum Neurotoxin A, Plos Pathog., 4(9), 1-9 (2008).
  91. J Zimmer, Y Nam, T Rapoport, Structure of a Complex of the ATPase SecA and the Protein-Translocation Channel, Nature, 455, 936-943 (2008).[ premier ]
  92. W Chen, S Lam, H Srinath, Z Jiang, J Correia, C Schiffer, K Fitzgerald, K Lin, W Royer, Jr., Insights into the Interferon Regulatory Factor Activation from the Crystal Structure of Dimeric IRF5, Nat. Struct. Mol. Biol., 15(11), 1213 (2008).[ premier ]
  93. L Cappadocia, J Sygusch, N Brisson, Purification, Crystallization and Preliminary X-ray Diffraction Analysis of the Whirly Domain of StWhy2 in Complex with Single-Stranded DNA, Acta Cryst. F, 64, 1056-1059 (2008).
  94. F Collard, J Zhang, I Nemet, K Qanungo, V Monnier, V Yee, Crystal Structure of the Deglycating Enzyme Fructosamine Oxidase (Amadoriase ll), J. Biol. Chem., 283, 27007-27016 (2008).
  95. U Samanta, B Bahnson, Crystal Structure of Human Plasma Platelet-Activating Factor Acetylhydrolase, J. Biol. Chem., 283, 31617-31624 (2008).
  96. H Wang, Z Yan, S Yang, J Cai, H Robinson, H Ke, Kinetic and Structural Studies of Phosphodiesterase-8A and Implication on the Inhibitor Selectivity, Biochemistry, 47, 12760-12768 (2008).
  97. L Jones, L Colf, A Bankovich, J Stone, Y Gao, C Chan, R Huang, K Garcia, D Kranz, Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors, Biochemistry, 47, 12398-12408 (2008).
  98. D Dowling, S Gantt, S Gattis, C Fierke, D Christianson, Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors, Biochemistry, 47, 13554-13563 (2008).
  99. S Messing, Structure and Function of the RNA Pyrophosphohydrolase BdRppH and the 9-cis-epoxy Carotenoid Dioxygenase VP14 , Ph.D Thesis. Johns Hopkins University, Baltimore (2008).
  100. B Nolen, T Pollard, Structure and Biochemical Properties of Fission Yeast Arp2/3 Complex Lacking the Arp2 Subunit, J. Biol. Chem., 283(39), 26490-8 (2008).
  101. Y Pan, J Weng, V Kabaleeswaran, H Li, Y Cao, R Bholse, M Zhou, Cortisone Dissociates the Shaker Family K Channels from their Beta Subunit, Nat. Chem. Biol., 4(11), 708-714 (2008).[ premier ]
  102. C Ng, R Jackson, J Buschdorf, Q Sun, G Guy, J Sivaraman, Structural Basis for a Novel Intrapeptidyl H-bond and Reverse Binding of c-Cbl-TKB Domain Substrates, EMBO J., 27(5), 804-16 (2008).[ premier ]
  103. W Zhang, Y Cho, E Lolis, J Howe, Structural and Single-Channel Results Indicate that the Rates of Ligand Binding Domain Closing and Opening Directly Impact AMPA Receptor Gating, J. Neurosci., 28(4), 932 (2008).[ premier ]
  104. W Martucci, M Vargo, K Anderson, Explaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase, Biochemistry, 47(34), 8902-8911 (2008).
  105. H Schubert, J Phillips, A Heroux, C Hill, Structure and Mechanistic Implications of a Uroporphyrinogen III Synthase−Product Complex, Biochemistry, 47(33), 8648-8655 (2008).
  106. I Lee, H Schindelin, Structural Insights into E1-Catalyzed Ubiquitin Activation and Transfer to Conjugating Enzymes, Cell, 134(2), 268-278 (2008).[ premier ]
  107. S Biswas, M Mohammad, L Movileanu, B van den Berg, Crystal Structure of the Outer Membrane Protein OpdK from Pseudomonas aeruginosa, Structure, 16(7), 1027-1035 (2008).
  108. H Demirci, S Gregory, A Dahlberg, G Jogl, Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase, Structure, 16(7), 1059-1066 (2008).
  109. S Altieri, G Clayton, W Silverman, A Olivares, E De La Cruz, L Thomas, J Morais-Cabral, Structural and Energetic Analysis of Activiation by a Cyclic Nucleotide Binding Domain, J. Mol. Biol., 381(3), 655-669 (2008).
  110. E Lazar-Molnar, Q Yan, E Cao, U Ramagopal, S Nathenson, S Almo, Crystal Structure of the Complex Between Programmed Death-1 (PD-1) and its Ligand PD-L2, Proc Natl Acad Sci USA, 105(30), 10483-10488 (2008).[ premier ]
  111. R Wing, S Bailey, T Steitz, Insights into the Replisome from the Structure of a Ternary Complex of the DNA, J. Mol. Biol., 382(4), 859-869 (2008).
  112. A Serganov, L Huang, D Patel, Structural Insights Into Amino Acid Binding and Gene Control by a Lysine Riboswitch, Nature, 455, 1263-1267 (2008).[ premier ]
  113. J Song, R Kingston, WDR5 Intearcts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket, J. Biol. Chem., 238(50), 35258 (2008).
  114. J Beierlein, K Frey, D Bolstad, P Pelphrey, T Joska, A Smith, N Priestley, D Wright, A Anderson, Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting Bacillus anthracis Dihydrofolate Reductase, J. Med. Chem., 51, 7532-7540 (2008).
  115. D Lietha, M Eck, Crystal Structures of the FAK Kinase in Complex with TAE226 and Related bis-anilino Pyrimidine Inhibitors Reveal a Helical DFG Conformation, PLoS One, 33(11), e3800 (2008).
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  117. B Manjasetty, A Turnbull, S Panjikar, K Bussow, M Chance, Automated Technologies and Novel Techniques to Accelerate Protein Crystallography for Structrual Genomics, Proteomics, 8, 612–625 (2008).[ premier ]
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[ premier ] - A publication is considered premier if the journal has an impact factor of 6 or greater (from Journal Citation Report 2003, Thomson Institute for Scientific Information). These journals represent approximately the top 3% of all journals. Two additional journals are included in the NSLS premier list, Applied Physics Letters (impact factor 4.0) and Environmental Sciences and Technology (impact factor 3.6), because these journals represent the "best in class" for the NSLS industrial and environmental science users, even though their impact factors are less than 6.