X29A Publications


Calendar Year
Total Pubs
Premier Pubs *
2010
2
1
2009
86
37
2008
93
30
2007
87
41
2006
50
24
2005
19
9
2004
2
2


  1. w Kim, A Sigalov, L Stern, Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRζ fragments, Acta Cryst. D, D66, 163-175 (2010).
  2. A Waight, J Love, D Wang, Structure and Mechanism of a Pentameric Formate Channel, Nat. Struct. Mol. Biol., 17, 31-37 (2010).[ premier ]
  3. M Swan, R Johnson, L Prakash, S Prakash, A Aggarwal, Structural Basis of High-Fidelity DNA Synthesis by Yeast DNA Polymerase δ, Nat. Struct. Mol. Biol., 16, 979-986 (2009).[ premier ]
  4. R Agarwal, J Schmidt, R Stafford, S Swaminathan, Mode of VAMP Substrate Recognition and Inhibition of Clostridium botulinum Neurotoxin F, Nat. Struct. Mol. Biol., 16(7), 789-794 (2009).[ premier ]
  5. A Bera, V Atanasova, H Robinson, E Eisenstein, J Coleman, E Pesci, J Parsons, Structure of PqsD, a Pseudomonas Quinolone Signal Biosynthetic Enzyme, in Complex with Anthranilate, Biochemistry, 48(36), 8644-55 (2009).
  6. S Bowley, N Okumura, S Lord, Impaired Protofibril Formation in Fibrinogen γN308K Is Due to Altered D:D and “A:a” Interactions, Biochemistry, 48, 8656–8663 (2009).
  7. C Zhan, Q Yan, Y Patskovsky, Z Li, R Toro, A Meyer, H Cheng, M Brenowitz, S Nathenson, S Almo, Biochemical and Structural Characterization of the Human TL1A Ectodomain, Biochemistry, 48, 7636–7645 (2009).
  8. Q Yin, B Lamothe, B Darnay, H Wu, Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2, Biochemistry, 48, 10558–10567 (2009).
  9. M Ho, M Cassera, D Madrid, L Ting, P Tyler, K Kim, S Almo, V Schramm, Structural and Metabolic Specificity of Methylthiocoformycin for Malarial Adenosine Deaminases, Biochemistry, 48, 9618–9626 (2009).
  10. K Smith, S Lipchock, T Ames, J Wang, R Breaker, S Strobel, Structural Basis of Ligand Binding by a C-di-GMP Riboswitch, Nat. Struct. Mol. Biol., 16, 1218-1223 (2009).[ premier ]
  11. A Tripathi, Y Ren, P Jeffrey, F Hughson, Structural Characterization of Tip20p and Dsl1p, Subunits of the Dsl1p Vesicle Tethering Complex, Nat. Struct. Mol. Biol., 16(2), 114 (2009).[ premier ]
  12. Z Zhou, J Zhen, N Karpowich, C Law, M Reith, D Wang, Antidepressant Specificity of Serotonin Transporter Suggested by Three LeuT-SSRI Structures, Nat. Struct. Mol. Biol., 16, 652-657 (2009).[ premier ]
  13. Y Zhang, R Cao, F Yin, M Hudock, R Guo, Y Song, J No, K Bergan, A Leon, Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR Investigation, J. Am. Chem. Soc., 131, 5153-5162 (2009).[ premier ]
  14. T Brandao, H Robinson, S Johnson, A Hengge, Impaired Acid Catalysis by Mutation of a Protein Loop Hinge Residue in a YopH Mutant Revealed by Crystal Structures, J. Am. Chem. Soc., 131(2), 778–786 (2009).[ premier ]
  15. M Swan, R Johnson, L Prakash, S Prakash, A Aggarwal, Structure of the Human Rev1–DNA–dNTP Ternary Complex, J. Mol. Biol., 390, 699–709 (2009).
  16. A Orville, G Lountos, S Finnegan, G Gadda, R Prabhakar, Crystallographic, Spectroscopic, and Computational Analysis of a Flavin C4a-Oxygen Adduct in Choline Oxidase, Biochemistry, 48, 720–728 (2009).
  17. D Xiang, C Xu, D Kumaran, A Brown, M Sauder, S Burley, S Swaminathan, F Raushel, Functional Annotation of Two New Carboxypeptidases from the Amidohydrolase Superfamily of Enzymes, Biochemistry, 48, 4567-4576 (2009).
  18. A Heroux, D Bozinovski, M Valley, P Fitzpatrick, A Orville, Crystal Structures of Intermediates in the Nitroalkane Oxidase Reaction, Biochemistry, 48, 3407-3416 (2009).
  19. J Cochrane, S Lipchock, K Smith, S Strobel, Structural and Chemical Basis for Glucosamine 6-Phosphate Binding and Activation of the glmS Ribozyme, Biochemistry, 48(15), 3239-3246 (2009).
  20. D Xiang, Y Patskovsky, C Xu, A Meyer, J Sauder, S Burley, S Almo, F Raushel, Functional Identification of Incorrectly Annotated Prolidases from the Amidohydrolase Superfamily of Enzymes, Biochemistry, 48(17), 3730–3742 (2009).
  21. G Blaha, R Stanley, T Steitz, Formation of the First Peptid Bond: the Structure of EF-P Bound to the 70S Ribosome, Science, 325, 966 (2009).[ premier ]
  22. G Clayton, S Aller, J Wang, V Unger, J Morais-Cabral, Combining Electron Crystallography and X-ray Crystallography to Study the MlotiK1 Cyclic Nucleotide-Regulated Potassium Channel, J. Struct. Biol., 167(3), 220-226 (2009).
  23. F Zhang, M Hu, G Tian, P Zhang, D Finley, P Jeffrey, Y Shi, Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii, Mol. Cell, 34(4), 473-484 (2009).[ premier ]
  24. T Schalch, G Job, V Noffsinger, S Shanker, C Kuscu, L Joshua-Tor, J Partridge, High Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3 is Required to Establish Centromeric Hterochromatin, Mol. Cell, 34, 36-46 (2009).[ premier ]
  25. Y Chung, T Brendler, S Austin, A Guarne, Structural Insights into the Cooperative Binding of SeqA to a Tandem GATC Repeat, Nucleic Acids Res., 37(10), 3143-52 (2009).[ premier ]
  26. J Jordan, J Arndt, K Hanf, G Li, J Hall, S Demarest, F Huang, X Wu, B Miller, Structural Understanding of Stabilization Patterns in Engineered Bispecific lg-like Antibody Molecules, Proteins: Struc. Func. Genet., 77(4), 832-841 (2009).
  27. D Gallagher, N Smith, S Kim, H Robinson, P Reddy, Protein Crystal Engineering of YpAC-IV Using a Strategy of Excess Charge Reduction, Cryst. Growth Des., 9(8), 3570–3574 (2009).
  28. T Wang, H Li, G Lin, C Tang, D Li, C Nathan, K Heran Darwin, Structural Insights on the Mycobacterium tuberculosis Proteasomal ATPase Mpa, Structure, 17, 1377–1385 (2009).
  29. M Navarro, N De, N Bae, Q Wang, H Sondermann, Structural Analysis of the GGDEF-EAL Domain-Containing c-di-GMP Receptor FimX, Structure, 17(8), 1104-1116 (2009).
  30. J Lulo, S Yuzawa, J Schlessinger, Crystal Structures of Free and Ligand-Bound Focal Adhesion Targeting Domain of Pyk2, Biochem. Biophys. Res. Commun., 383(3), 347-352 (2009).
  31. U Pieper, R Chiang, J Seffernick, S Brown, M Glasner, L Kelly, N Eswar, M Sauder, J Bonanno, Target Selection and Annotation for the Structural Genomics of the Amidohydrolase and Enolase Superfamilies, J. Struct. Funct. Genomics, 10(2), 107-125 (2009).
  32. U Samanta, C Wilder, B Bahnson, Crystallization and Preliminary X-Ray Crystallographic Analysis of Human Plasma Platelet Activating Factor Acetylhydrolase, Protein Peptide Lett., 16(1), 97-100 (2009).
  33. M Mitchell, H Nam, A Carter, A McCall, C Rence, A Bennett, B Gurda, R McKenna, M Porter, Production, Purification and Preliminary X-ray Crystallographic Studies of Adeno-Associated Virus Serotype 9, Acta Cryst. F, 65, 715–718 (2009).
  34. K Sippel, S Boehlein, Y Sakai, J Quirit, M Agbandje-McKenna, C Rosser, R McKenna, Cloning, Expression, Purification, Crystallization and Preliminary X-ray Analysis of Mycoplasma Genitalium Protein MG289, Acta Cryst. F, 65, 910-912 (2009).
  35. A Cheng, J Speir, Y Yuan, J Johnson, S Wong, Preliminary X-ray Data Analysis of Crystalline Hibiscus Chlorotic Ringspot Virus, Acta Cryst. F, 65(6), 589-593 (2009).
  36. H Zhao, A Heroux, R Sequeira, L Tang, Preliminary Crystallographic Studies of the Regulatory Domain of Response Regulator YycF from an Essential Two-Component Signal Transduction System, Acta Cryst. F, F65, 719-722 (2009).
  37. S Tulsidas, S Thangamani, B Ho, J Sivaraman, J Ding, Crystallization of a Nonclassical Kazal-type Carcinoscorpius Rotundicauda Serine Protease Inhibitor, CrSPI-1, Complexed with Subtilisin, Acta Cryst. F, 65(Pt 5), 533-535 (2009).
  38. L Matthews, A Duong, A Prasad, B Duncker, A Guarne, Crystallization and Preliminary X-ray Diffraction Analysis of motif N from Saccharomyces cerevisiae Dbf4, Acta Cryst. F, 65(9), 890-894 (2009).
  39. Q Han, H Robinson, T Cai, D Tagle, J Li, Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III, Mol. Cell. Bio., 29(3), 784-793 (2009).[ premier ]
  40. J Gutierrez, T Crowder, A Rinaldo-Matthis, M Ho, S Almo, V Schramm, Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing., Nat. Chem. Biol., 5(4), 251-257 (2009).[ premier ]
  41. C Jobichen, A Fernandis, A Velazquez-Campoy, K Leung, Y Mok, M Wenk, J Sivaraman, Identification and Characterization of the Lipid-Binding Property of GrlR, a Locus of Enterocyte Effacement Regulator, Biochem. J., 420(2), 191-199 (2009).
  42. J Woo, J Lim, H Shin, M Suh, B Ku, H Lee, K Joo, H Robinson, J Lee, Structural Studies of a Bacterial Condensin Complex Reveal ATP-Dependent Disruption of Intersubunit Interactions, Cell, 136, 85–96 (2009).[ premier ]
  43. F Scott, B Stec, C Pop, M Dobaczewska, J Lee, E Monosov, H Robinson, G Salvesen, R Schwarzenbacher, S Riedl, The Fas-FADD Death Domain Complex Structure Unravels Signalling by Receptor Clustering, Nature, 457, 1019-1022 (2009).[ premier ]
  44. Q Han, H Robinson, T Cai, D Tagle, J Li, Structural Insight into the Inhibition of Human Kynurenine Aminotransferase I/Glutamine Transaminase K, J. Med. Chem., 52, 2786-2793 (2009).
  45. C Quezada, S Hicks, J Galan, C Stebbins, A Family of Salmonella Virulence Factors Functions as a Distinct Class of Autoregulated E3 Ubiquitin Ligases, Proc Natl Acad Sci USA, 106, 4864-4869 (2009).[ premier ]
  46. T Garrett, A Burgess, H Gan, R Luwor, G Cartwright, F Walker, S Orchard, A Clayton, E Nice, Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR, Proc Natl Acad Sci USA, 106, 5082-5087 (2009).[ premier ]
  47. M Ho, J Menetret, H Tsuruta, K Allen, The Origin of the electrostatic Perturbation in Acetoacetate Decarboxylase, Nature, 459, 393 (2009).[ premier ]
  48. E Hearn, D Patel, D Lepore, M Indic, B van den Berg, Transmembrane Passage of Hydrophobic Compounds Through a Protein Channel Wall, Nature, 458, 367-370 (2009).[ premier ]
  49. Y Fang, H Jayaram, T Shane, L Partensky, F Wu, C williams, Y Xiong, C Miller, Structure of a Prokaryotic Virtual Proton Pump at 3.2 Ε Resolution, Nature, 460, 1040-1043 (2009).[ premier ]
  50. A Serganov, L Huang, D Patel, Coenzyme Recognition and Gene Regulation by a Flavin Mononucleotide Riboswitch, Nature, 458, 233-237 (2009).[ premier ]
  51. H Li, Structural and Biochemical Studies of TIGAR and ZnuA, Ph.D. Thesis. Brown University, Providence (2009).
  52. G Buchko, Pentapeptide Repeat Proteins and Cyanobacteria, Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications, p. 233-257, Nova Science Publishers, Inc., New York (2009).
  53. G Buchko, H Robinson, A Addlagatta, Structural Characterization of the Protein cce_0567 from Cyanothece 51142, a Metalloprotein Associated with Nitrogen Fixation in the DUF683 Family, Biochim Biophys Acta, 1794(4), 627-633 (2009).
  54. E Burgos, M Ho, S Almo, V Schramm, A Phosphoenzyme Mimic, Overlapping Catalytic Sites and Reaction Coordinate Motion for Human NAMPT, Proc Natl Acad Sci USA, 106(33), 13748–13753 (2009).[ premier ]
  55. H Seo, Y Ma, E Debler, D Wacker, S Kutik, G Blobel, A Hoelz, Structural and Functional Analysis of Nup120 Suggests Ring Formation of the Nup84 Complex, Proc Natl Acad Sci USA, 106, 14281-14286 (2009).[ premier ]
  56. Q Wang, M Navarro, G Peng, E Molinelli, G Lin, B Judson, K Rajashankar, H Sondermann, Molecular Mechanism of Membrane Constriction and Tubulation Mediated by the F-BAR Protein Pacsin/Syndapin, Proc Natl Acad Sci USA, 106(31), 12700-12705 (2009).[ premier ]
  57. B Ibrahim, N Kanneganti, G Rieckhof, A Das, D Laurents, J Palenchar, V Bellofatto, D Wah, Structure of the C-terminal Domain of Transcription Facto IIB from Trypanosoma brucei, Proc Natl Acad Sci USA, 106, 13242-7 (2009).[ premier ]
  58. P Kiser, M Golczak, D Lodowski, M Chance, K Palczewski, Crystal Structure of Native RPE65, the Retinoid Isomerase of the Visual Cycle, Proc Natl Acad Sci USA, 106, 17325–17330 (2009).[ premier ]
  59. A Gelinas, M Paschini, F Reyes, A Heroux, R Batey, V Lundblad, D Wuttke, Telomere Capping Proteins are Structurally Related to RPA with an additional Telomere-Specific Domain, Proc Natl Acad Sci USA, 106(46), 19298-19303 (2009).[ premier ]
  60. V Nagy, K Hsia, E Debler, M Kampmann, A Davenport, G Blobel, A Hoelz, Structure of a Trimeric Nucleoporin Complex Reveals Alternate Oligomerization States, Proc Natl Acad Sci USA, 106(42), 17696-17698 (2009).[ premier ]
  61. E Levin, M Quick, M Zhou, Crystal Structure of a Bacterial Homologue of the Kidney Urea Transporter, Nature, 462, 757-761 (2009).[ premier ]
  62. L Dang, D White, S Gross, B Bennett, M Bittinger, E Driggers, V Fantin, H Jang, S Jin, Cancer-Associated IDH1 Mutations Produce 2-hydroxyglutarate, Nature, 462, 739-744 (2009).[ premier ]
  63. Y Qi, M Spong, K Nam, A Banerjee, S Jiralerspong, M Karplus, G Verdine, Encounter and Extrusion of an Intrahelical Lesion by a DNA Repair Enzyme, Nature, 462, 762-766 (2009).[ premier ]
  64. G Lin, D Li, L Sorio de Carvalho, H Deng, H Tao, G Vogt, K Wu, J Schneider, T Chidawanyika, Inhibitors Selective for Mycobacterial Versus Human Proteasomes, Nature, 461, 621-627 (2009).[ premier ]
  65. S Xiang, A Cooper-Morgan, X Jiao, M Kiledjian, J Manley, L Tong, Structure and Function of the 5'->3' Exoribonuclease Rat1 and its Activating Partner Rai1, Nature, 458, 784-788 (2009).[ premier ]
  66. B Nolen, N Tomasevic, A Russell, D Pierce, Z Jia, C McCormick, J Hartman, R Sakowicz, T Pollard, Characterization of Two Classes of Small Molecule Inhibitors of Arp2/3 Complex, Nature, 460, 1031-1034 (2009).[ premier ]
  67. Y Ren, C Yip, A Tripathi, D Huie, P Jeffrey, T Walz, F Hughson, A Structure-Based Mechanism for Vesicle Capture by the Multisubunit Tethering Complex Dsl1, Cell, 139(6), 1119-1129 (2009).[ premier ]
  68. C Chou, L Yu, L Tong, Crystal Structure of Biotin Carboxylase in Complex with Substrates and Implications for Its Catalytic Mechanism, J. Biol. Chem., 284, 11690-11697 (2009).
  69. O Ezezika, N Younger, J Lu, D Kaiser, Z Corbin, B Nolen, D Kovar, T Pollard, Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: Insights from Crystal Structures of Fission Yeast Proflin, J. Biol. Chem., 284(4), 2088-2097 (2009).
  70. Y Tan, S Chan, T Ong, L Yit, Y Tiong, F Chew, J Sivaraman, Y Mok, Structures of Two Major Allergens, Bla g 4 and Per a 4, From Cockroaches and Their IgE Binding Epitopes, J. Biol. Chem., 284, 3148-3157 (2009).
  71. J Lafrance-Vanasse, M Lefebvre, P Di Lello, J Sygusch, J Omichinski, Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-Bound Forms, J. Biol. Chem., 284, 938-944 (2009).
  72. P Pattanaik, C Bethel, A Hujer, K Hujer, A Distler, M Taracila, V Anderson, T Fritsche, R Jones, Strategic Design of an Effective beta-Lactamase Inhibitor, J. Biol. Chem., 284, 945-953 (2009).
  73. D Gallagher, N Smith, S Kim, H Robinson, P Reddy, Profound Asymmetry in the Structure of the cAMP-free cAMP Receptor Protein (CRP) from Mycobacterium tuberculosis, J. Biol. Chem., 284, 8228–8232 (2009).
  74. K Chattopadhyay, U Ramagopal, S Nathenson, S Almo, 1.8 Ε Structure of Murine GITR Ligand Dimer Expressed in Drosophila Melanogaster S2 Cells, Acta Cryst. D, 65(5), 434-439 (2009).
  75. V Nayak, M Dessau, K Kucera, K Anthony, M Ledizet, Y Modis, Crystal Structure of Dengue Type 1 Envelope Protein in the Postfusion Conformation and its Implication for Receptor Binding, Membrane Fusion and Antibody Recognition, J. Virology, 83, 4338 (2009).
  76. E Karakas, N Simorowski, H Furukawa, Structure of the Zinc-Bound Amino-Terminal Domain of the NMDA Receptor NR2B Subunit, EMBO J., 28, 3910–3920 (2009).[ premier ]
  77. G Gurel, G Blaha, P Moore, U2504 Determines the Species Specificity of the A-site Cleft Antibiotics: The sStructures of Tiamulin, Homoharringtonine and Bruceantin Bound to the Ribosome, J. Mol. Biol., 389, 146-156 (2009).
  78. K Frey, J Liu, M Lombardo, D Bolstad, D Wright, A Anderson, Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternative Conformation of NADPH that may be Linked to Trimethoprim Resistance, J. Mol. Biol., 387, 1298-1308 (2009).
  79. G Yang, A Bolotnikov, Y Cui, G Camarda, A Hossain, R James, Impurity Gettering Effect of Te Inclusions in Cdznte Single Crystals, J. Cryst. Growth, 311(1), 99-102 (2009).
  80. Y Li, C Cao, W Jia, L Yu, M Mo, Q Wang, Y Huang, J Lim, M Ishihara, Structure of the F-Spondin Domain of Mindin, an Integrin Ligand and Pattern Recognition Molecule, EMBO J., 28(3), 286-297 (2009).[ premier ]
  81. J Liu, D Bolstad, A Smith, N Priestley, D Wright, A Anderson, Probing the Active Site of Candida Glabrata Dihydrofolate Reductase with High Resolution Crystal Structures and the Synthesis of New Inhibitors, Chem. Biol. Drug Des., 73, 62-74 (2009).
  82. S Li, X Tang, J Seetharaman, C Yang, Y Gu, J Zhang, H Du, J Shih, C Hew, Diminerization of Hepatitis E Virus Capsid Protein E2s Domain is Essential for Virus-Host Interaction, Plos Pathog., 5(8), 1-10 (2009).
  83. J Drumm, K Mi, P Bilder, M Sun, J Lim, H Bielefeldt-Ohmann, R Basaraba, M So, G Zhu, Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP Binding: Requirement for Establishing Chronic Persistent Infection, Plos Pathog., 5(5), 460 (2009).
  84. Q Han, T Cai, D Tagle, H Robinson, J Li, Substrate Specificity and Structure of Human aminoadipate aminotransferase/kynurenine aminotransferase II, Bioscience Rep., 28(4), 205-215 (2009).
  85. L Clark, P Boriack-Sjodin, E Day, J Eldredge, C Fitch, M Jarpe, S Miller, Y Li, K Simon, H van Vlijmen, An Antibody Loop Replacement Design Feasibility Study and a Loop-Swapped Dimer Structure, Protein Eng. Des. Sel., 22(2), 93-101 (2009).
  86. H Lim, C Miller, Intracellular Proton-Transfer Mutants in a CLC Cl–/H+ Exchanger, J Gen. Physiol., 133, 131-138 (2009).
  87. T Castano, H Wang, N Campillo, S Ballester, C Gonzalez-Garcia, J Hernandez, C Perez, J Cuenca, A Perez-Castillo, Synthesis, Structural Analysis, and Biological Evaluation of Thioxoquinazoline Derivatives as Phosphodiesterase 7 Inhibitors, ChemMedChem, 4, 866-876 (2009).
  88. J Alvarado, A Nemkal, J Sauder, M Russell, D Akiyoshi, W Shi, S Almo, L Weiss, Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470, 168, 158–167 (2009).
  89. H Wang, M Ye, H Robinson, S Francis, H Ke, Conformational Variations of Both Phosphodiesterase-5 and Inhibitors Provide the Structural Basis for the Physiological Effects of Verdenafil and Sildenafil, Mol. Pharmacol., 73, 104-110 (2008).
  90. G Chen, H Wang, H Robinson, J Cai, Y Wan, H Ke, An Insight into the Pharmacophores of Phosphodiesterase-5 Inhibitors from Synthetic and Crystal Structural Studies, Biochem. Pharmacol., 75(9), 1717-1728 (2008).
  91. Q Han, T Cai, D Tagle, H Robinson, J Li, Substrate Specificity and Structure of Human Aminoadipate Aminotransferase/kynurenine Aminotransferase II, Bioscience Rep., 28(4), 205-215 (2008).
  92. D Kumaran, R Rawat, A Ahmed, S Swaminathan, Substrate Binding Mode and its Implication on Drug Design for Botulinum Neurotoxin A, Plos Pathog., 4(9), 1-9 (2008).
  93. D Lietha, M Eck, Crystal Structures of the FAK Kinase in Complex with TAE226 and Related bis-anilino Pyrimidine Inhibitors Reveal a Helical DFG Conformation, PLoS One, 33(11), e3800 (2008).
  94. T Chua, J Bujnicki, T Tan, F Huynh, B Patel, J Sivaraman, Y Ogimoto, K Miyano, H Sawa, The Structure of Sucrose Phosphate Synthase from Halothermothrix orenii Reveals Its Mechanism of Action and Binding Mode, Plant Cell, 20, 1059-1072 (2008).[ premier ]
  95. L Velloso, S Bhaskaran, R Schuch, V Fischetti, C Stebbins, A Structural Basis for the Allosteric Regulatin of Non-Hydrolysing UDP-G1cNAc 2-Epimerases, EMBO Rep., 9(2), 199-205 (2008).[ premier ]
  96. B Manjasetty, A Turnbull, S Panjikar, K Bussow, M Chance, Automated Technologies and Novel Techniques to Accelerate Protein Crystallography for Structrual Genomics, Proteomics, 8, 612–625 (2008).[ premier ]
  97. E Rangarajan, A Asinas, A Proteau, C Munger, j Baardsnes, P Iannuzzi, A Matte, m Cygler, Structure of [NiFe] Hydrogenase Maturation Protein HypE from Escherichia coli and its Interaction with HypF, J. Bacteriol., 190(4), 1447-1458 (2008).
  98. P Pallan, D Ittig, A Heroux, Z Wawrzak, C Leumann, M Egli, Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles, Chem. Commun., 7, 883-885 (2008).
  99. C Ng, R Jackson, J Buschdorf, Q Sun, G Guy, J Sivaraman, Structural Basis for a Novel Intrapeptidyl H-bond and Reverse Binding of c-Cbl-TKB Domain Substrates, EMBO J., 27(5), 804-16 (2008).[ premier ]
  100. D Lee, J Zheng, Y She, Z Jia, Structure of Escherichia coli tyrosine Kinase Etk Reveals a Novel Activation Mechanism, EMBO J., 27, 1758-1766 (2008).[ premier ]
  101. J Song, J Garlick, R Kingston, Structural Basis of Histone H4 Recognition by p55, Genes Dev., 22, 1313 (2008).[ premier ]
  102. K Siu, J Lee, J Sufrin, B Moffatt, M McMillan, K Cornell, C Isom, L Howell, Molecular Determinants of Substrate Specificity in Plant 5'-Methylthioadenosine Nucleosidases, J. Mol. Biol., 378(1), 112-128 (2008).
  103. S Johnson, D Close, H Robinson, I Vallet-Gely, S Dove, C Hill, Crystal Structure and RNA Binding of the Tex Protein from Pseudomonas aeruginosa, J. Mol. Biol., 377(5), 1460-1473 (2008).
  104. R Wing, S Bailey, T Steitz, Insights into the Replisome from the Structure of a Ternary Complex of the DNA, J. Mol. Biol., 382(4), 859-869 (2008).
  105. Q Cui, T Sulea, J Schrag, C Munger, M Hung, M Naim, M Cygler, E Purisima, Molecular Dynamics - Solvated Interaction Energy Studies of Protein-Protein Interactions; The MP1-p14 Scaffolding Complex, J. Mol. Biol., 379(4), 787-802 (2008).
  106. G Blaha, G Gurel, S Schroeder, P Moore, T Steitz, Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant, J. Mol. Biol., 379(3), 505-519 (2008).
  107. Y Hsu, G Jubelin, F Taieb, J Nougayrθde, E Oswald, C Stebbins, Structure of the Cyclomodulin Cif from Pathogenic Escherichia coli, J. Mol. Biol., 384(2), 465-477 (2008).
  108. S Altieri, G Clayton, W Silverman, A Olivares, E De La Cruz, L Thomas, J Morais-Cabral, Structural and Energetic Analysis of Activiation by a Cyclic Nucleotide Binding Domain, J. Mol. Biol., 381(3), 655-669 (2008).
  109. S Sunita, K Tkaczuk, E Purta, J Kasprzak, S Douthwaite, J Bujnicki, J Sivaraman, Crystal Structure of the Escherichia coli 23S rRNA: m{5}C Methyltransferase RlmI (YccW) Reveals Evolutionary Links Between RNA Modification Enzymes, J. Mol. Biol., 383(3), 652-666 (2008).
  110. D Kamir, S Zierow, L Leng, Y Cho, Y Diaz, J Griffith, C McDonald, M Merk, R Mitchell, A Leishmania Ortholog of Macrophage Migration Inhibitory Factor Modulates Host Macrophage Responses, J. Immunol., 180, 8250-8261 (2008).[ premier ]
  111. W Zhang, Y Cho, E Lolis, J Howe, Structural and Single-Channel Results Indicate that the Rates of Ligand Binding Domain Closing and Opening Directly Impact AMPA Receptor Gating, J. Neurosci., 28(4), 932 (2008).[ premier ]
  112. B Stanley, E Ehrlich, L Short, Y Yu, Z Xiao, X Yu, Y Xiong, Structural Insight into the Human Immunodeficiency Virus Vif SOCS Box and Its Role in Human E3 Ubiquitin Ligase Assembly, J. Virology, 82(17), 8656-8663 (2008).
  113. J Shi, J Sivaraman, J Song, Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease, J. Virology, 82(9), 4620-4629 (2008).
  114. F Collard, J Zhang, I Nemet, K Qanungo, V Monnier, V Yee, Crystal Structure of the Deglycating Enzyme Fructosamine Oxidase (Amadoriase ll), J. Biol. Chem., 283, 27007-27016 (2008).
  115. U Samanta, B Bahnson, Crystal Structure of Human Plasma Platelet-Activating Factor Acetylhydrolase, J. Biol. Chem., 283, 31617-31624 (2008).
  116. L Di Costanzo, J Drury, T Penning, D Christianson, Crystal Structure of Human Liver delta {4}-3-Ketosteroid 5 beta-Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis, J. Biol. Chem., 283(24), 16830-16839 (2008).
  117. Q Han, H Robinson, J Li, Crystal Structure of Human Kynurenine Aminotransferase ll*, J. Biol. Chem., 283(6), 3567-3573 (2008).
  118. L Deng, S Cho, E Malchiodi, M Kerzic, J Dam, R Mariuzza, Molecular Architecture of the Major Histocompatibility Complex Class I-Binding Site of Ly49 Natural Killer Cell Receptors, J. Biol. Chem., 283(24), 16840-16849 (2008).
  119. B Nolen, T Pollard, Structure and Biochemical Properties of Fission Yeast Arp2/3 Complex Lacking the Arp2 Subunit, J. Biol. Chem., 283(39), 26490-8 (2008).
  120. A Taylor, G Hu, P Hart, L McAlister-Henn, Allosteric Motions in Structures of Yeast NAD+-Specific Isocitrate Dehydrogenase, J. Biol. Chem., 283(16), 10872-10880 (2008).
  121. R Agarwal, S Burley, S Swaminathan, Structure of Human Dual Specificity Protein Phosphatase 23, VHZ, Enzyme-Substrate/Product Complex, J. Biol. Chem., 283(14), 8946-8953 (2008).
  122. D Kumaran, R Rawat, M Ludivico, S Ahmed, S Swaminathan, Structure- and Substrate- Based Inhibitor Design for Clostridium botulinum Neurotoxin Serotype A* , J. Biol. Chem., 283, 18883 - 18891 (2008).
  123. K Jamieson, J Wu, S Hubbard, D Meruelo, Crystal Structure of the Human Laminin Receptor Precursor, J. Biol. Chem., 283(6), 3002-3005 (2008).
  124. M Salameh, A Soares, A Hockla, E Radisky, Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin, J. Biol. Chem., 283(7), 4115 (2008).
  125. J Song, R Kingston, WDR5 Intearcts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket, J. Biol. Chem., 238(50), 35258 (2008).
  126. Y Xu, l Feng, P Jeffrey, Y Shi, F Morel, Structure and Metal Exchange in the Cadmium Carbonic anhydrase of Marine Diatoms, Nature, 452, 56 (2008).[ premier ]
  127. A Serganov, L Huang, D Patel, Structural Insights Into Amino Acid Binding and Gene Control by a Lysine Riboswitch, Nature, 455, 1263-1267 (2008).[ premier ]
  128. X Ma, Structural Studies of Soluble Guanylyl Cyclase and its Bacterial Homologs, Ph.D. Thesis. Case Western Reserve University, Cleveland (2008).
  129. T Moldoveanu, K Gehring, D Green, Concerted Multi-Pronged Attack by Calpastatin to Occlude the Catalytic Cleft of Heterodimeric Calpains, Nature, 456, 404-408 (2008).[ premier ]
  130. E Lazar-Molnar, Q Yan, E Cao, U Ramagopal, S Nathenson, S Almo, Crystal Structure of the Complex Between Programmed Death-1 (PD-1) and its Ligand PD-L2, Proc Natl Acad Sci USA, 105(30), 10483-10488 (2008).[ premier ]
  131. H Jayaram, A Accardi, F Wu, C Williams, C Miller, Ion Permeation Through a Cl--Selective Channel Designed from a CLC Cl-/H+ Exchanger, Proc Natl Acad Sci USA, 105, 11194-11199 (2008).[ premier ]
  132. G Clayton, S Latieri, L Heginbotham, V Unger, J Morais-Cabral, Structure of the Transmembrane Regions of a Bacterial Cyclic Nucleotide-Regulated Channel, Proc Natl Acad Sci USA, 105(5), 1511-1515 (2008).[ premier ]
  133. S Chowdhury, L Joseph, S Kumar, S Tulsidas, S Bhat, E Ziomek, R Menard, J Sivaraman, E Purisima, Exploring Inhibitor Binding at the S' Subsites of Cathepsin L, J. Med. Chem., 51(5), 1361-8 (2008).
  134. J Clemente, A Robbins, P Grana, M Paleo, J Correa, M Villaverde, F Sardina, L Govindasamy, M Agbandje-McKenna, Design, Synthesis, Evaluation, and Crystallographic-Based Structural Studies of HIV-1 Protease Inhibitors with Reduced Response to the V82A Mutation, J. Med. Chem., 51, 852-860 (2008).
  135. S Zheng, G Kaur, H Wang, M Li, M MacNaughtan, X Yang, S Reid, J Prestegard, B Wang, Design, Synthesis, and Structure-Activity Relationship, Molecular Modeling, and NMR Studies of a Series of a Phenyl Alkyl Ketones as Highly Potent and Selective Phosphodiesterase-4 Inhibitors, J. Med. Chem., 51(24), 7673-7688 (2008).
  136. J Zimmer, Y Nam, T Rapoport, Structure of a Complex of the ATPase SecA and the Protein-Translocation Channel, Nature, 455, 936-943 (2008).[ premier ]
  137. S Messing, Structure and Function of the RNA Pyrophosphohydrolase BdRppH and the 9-cis-epoxy Carotenoid Dioxygenase VP14 , Ph.D Thesis. Johns Hopkins University, Baltimore (2008).
  138. J Beierlein, K Frey, D Bolstad, P Pelphrey, T Joska, A Smith, N Priestley, D Wright, A Anderson, Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting Bacillus anthracis Dihydrofolate Reductase, J. Med. Chem., 51, 7532-7540 (2008).
  139. I Lee, H Schindelin, Structural Insights into E1-Catalyzed Ubiquitin Activation and Transfer to Conjugating Enzymes, Cell, 134(2), 268-278 (2008).[ premier ]
  140. Y Xing, Z Li, Y Chen, J Stock, P Jeffrey, Y Shi, Structural Mechanism of Demethylation and Inactivation of Protein Phosphatase 2A, Cell, 133(1), 154-163 (2008).[ premier ]
  141. M Sherawat, D Tolan, K Allen, Structure of a Rabbit Muscle Fructose-1,6-Bisphosphate Aldolase A Dimer Variant, Acta Cryst. D, 64, 543-550 (2008).
  142. X Zhou, T Tan, S Valiyaveettil, M Go, R Kini, A Velazquez-Campoy, J Sivaraman, Structural Characterization of Myotoxic Ecarpholin S From Echis carinatus Venom, Biophys. J., 95, 3366–3380 (2008).
  143. Y Pan, J Weng, V Kabaleeswaran, H Li, Y Cao, R Bholse, M Zhou, Cortisone Dissociates the Shaker Family K Channels from their Beta Subunit, Nat. Chem. Biol., 4(11), 708-714 (2008).[ premier ]
  144. L Cappadocia, J Sygusch, N Brisson, Purification, Crystallization and Preliminary X-ray Diffraction Analysis of the Whirly Domain of StWhy2 in Complex with Single-Stranded DNA, Acta Cryst. F, 64, 1056-1059 (2008).
  145. P Mazumdar, D Kumaran, S Swaminathan, A Das, A Novel Acetate-Bound Complex of Human Carbonic Anhydrase ll, Acta Cryst. F, 64, 163-166 (2008).
  146. S Ragumani, D Kumaran, S Burley, S Swaminathan, Crystal Structure of a Putative Lysostaphin Peptidase from Vibrio cholerae, Proteins: Struc. Func. Bioinformatics, 72(3), 1096-1103 (2008).
  147. K Rao, S Burley, S Swaminathan, Crystal Structure of Conserved Protein of Unknown Function (MJ1651) from Methanococcus jannaschii, Proteins: Struc. Func. Bioinformatics, 70(2), 572-577 (2008).
  148. X Zhou, Q Sun, R Kini, J Sivaraman, A Universal Method for Fishing Target Proteins from Mixtures of Biomolecules using Isothermal Titration Calorimetry, Protein Sci., 17(10), 1798-1804 (2008).
  149. Y Tan, H Yu, K Leung, J Sivaraman, Y Mok, Structure of AscE and Induced Burial Regions in AscE and AscG upon Formation of the Chaperone Needle-subunit Complex of Type III Secretion System in Aeromonas Hydrophila, Protein Sci., 17(10), 1748-1760 (2008).
  150. W Metzler, J Yanchunas, C Weigelt, K Kish, H Klei, D Xie, Y Zhang, M Corbett, J Tamura, Involvement of DPP-IV Catalytic Residues in Enzyme-Saxagliptin Complex Formation, Protein Sci., 17, 240-250 (2008).
  151. J Chi Ki Ngo, M Huang, D Roth, B Furie, B Furie, Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex, Structure, 16(4), 597-606 (2008).
  152. S Biswas, M Mohammad, L Movileanu, B van den Berg, Crystal Structure of the Outer Membrane Protein OpdK from Pseudomonas aeruginosa, Structure, 16(7), 1027-1035 (2008).
  153. H Demirci, S Gregory, A Dahlberg, G Jogl, Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase, Structure, 16(7), 1059-1066 (2008).
  154. D Benarroch, P Smith, S Shuman, Characterization of a Trifunctional Mimivirus mRNA Capping Enzyme and Crystal Structure of the RNA Triphosphatase Domain, Structure, 16(4), 501-512 (2008).
  155. C Smits, P Czabotar, M Hinds, C Day, Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1, Structure, 16(5), 818-829 (2008).
  156. D Sidote, C Barbieri, T Wu, A Stock, Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of Binding, Structure, 16(5), 727-735 (2008).
  157. X Hu, H Wang, H Ke, B Kuhlman, Computer-Based Redesign of a Beta Sandwich Protein Suggests That Extensive Negative Design is not Required for de novo beta Sheet Design, Structure, 16(12), 1799-805 (2008).
  158. E Debler, Y Ma, H Seo, K Hsia, T Noriega, G Blobel, A Hoelz, A Fence-like Coat for the Nuclear Pore Membrane, Mol. Cell, 32, 815–826 (2008).[ premier ]
  159. Y Xu, Y Chen, P Zhang, P Jeffrey, Y Shi, Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation, Mol. Cell, 31, 873–885 (2008).[ premier ]
  160. G Buchko, H Robinson, H Pakrasi, M Kennedy, Insights into the Structural Variation Between Pentapeptide Repeat Proteins - Crystal Structure of Rfr23 from Cyanothece 51142, J. Struct. Biol., 162(1), 184-192 (2008).
  161. R Wilson, J Pata, Structural Insights into the Generation of Single-Base Deletions by the Y Family DNA Polymerase Dbh, Mol. Cell, 29(6), 767-779 (2008).[ premier ]
  162. N Toor, K Keating, S Taylor, A Pyle, Crystal Structure of a Self-Spliced Group ll Intron, Science, 320, 77 (2008).[ premier ]
  163. S Singh, C Piscitelli, A Yamashita, E Gouaux, A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation, Science, 322, 1655-1661 (2008).[ premier ]
  164. H Wang, Z Yan, S Yang, J Cai, H Robinson, H Ke, Kinetic and Structural Studies of Phosphodiesterase-8A and Implication on the Inhibitor Selectivity, Biochemistry, 47, 12760-12768 (2008).
  165. L Jones, L Colf, A Bankovich, J Stone, Y Gao, C Chan, R Huang, K Garcia, D Kranz, Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors, Biochemistry, 47, 12398-12408 (2008).
  166. D Dowling, S Gantt, S Gattis, C Fierke, D Christianson, Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors, Biochemistry, 47, 13554-13563 (2008).
  167. A Rinaldo-Matthis, A Murkin, U Ramagopal, K Clinch, S Mee, G Evans, P Tyler, R Furneaux, S Almo, v Schramm, L-Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase, J. Am. Chem. Soc., 130, 842-844 (2008).[ premier ]
  168. Q Han, Y Gao, H Robinson, J Li, Structural Insight into the Mechanism of Substrate Specificity of Aedes Kynurenine Aminotransferase, Biochemistry, 47, 1622-1630 (2008).
  169. V Malashkevich, K Varney, S Garrett, P Wilder, D Knight, T Charpentier, U Ramagopal, S Almo, D Weber, A Bresnick, Structure of Ca2+ -Bound S100A4 and Its Interaction With Peptides Derived from Nonmuscle Myosin-IIA, Biochemistry, 47, 5111-5126 (2008).
  170. B Greenhagen, K Shi, H Robinson, S Gamage, A Bera, J Ladner, J Parsons, Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS, Biochemistry, 47, 5281-5289 (2008).
  171. S Bowley, B Merenbloom, A Heroux, L Betts, N Okumura, O Gorkun, S Lord, Polymerization-Defective Fibrinogen Variant gammaD364A Binds Knob “A” Peptide Mimic, Biochemistry, 47(33), 8607-13 (2008).
  172. G Meinke, C Ezeokonkwo, P Balbo, W Stafford, C Moore, A Bohm, Structure of Yeast Poly(A) Polymerase in Complex with a Peptide from Fip1, an Intrinsically Disordered Protein, Biochemistry, 47, 6859–6869 (2008).
  173. W Martucci, M Vargo, K Anderson, Explaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase, Biochemistry, 47(34), 8902-8911 (2008).
  174. H Schubert, J Phillips, A Heroux, C Hill, Structure and Mechanistic Implications of a Uroporphyrinogen III Synthase−Product Complex, Biochemistry, 47(33), 8648-8655 (2008).
  175. W Chen, S Lam, H Srinath, Z Jiang, J Correia, C Schiffer, K Fitzgerald, K Lin, W Royer, Jr., Insights into the Interferon Regulatory Factor Activation from the Crystal Structure of Dimeric IRF5, Nat. Struct. Mol. Biol., 15(11), 1213 (2008).[ premier ]
  176. P Kumar, Y Yao, R Sternglanz, S Johnston, L Joshua-Tor, NADP Regulates the Yeast GAL Induction System, Science, 319, 1090-1092 (2008).[ premier ]
  177. Q Huai, A Zhou, L Lin, A Mazar, G parry, J Callahan, D Shaw, B Furie, B Furie, M Huang, Crystal Structures of Two Human Vitronectin, Urokinase and Urokinase Receptor Complexes, Nat. Struct. Mol. Biol., 15(4), 422 (2008).[ premier ]
  178. S Xiang, L Tong, Crystal Structures of Human and Staphylococcus aureus Pyruvate Carboxylase and Molecular Insights into the Carboxyltransfer Reaction, Nat. Struct. Mol. Biol., 15(3), 295-302 (2008).[ premier ]
  179. J Chao, Y Patskovsky, S Almo, R Singer, Structural Basis for the Coevolution of a Viral RNA-Protein Complex, Nat. Struct. Mol. Biol., 15(1), 103 (2008).[ premier ]
  180. A Tocilj, C Munger, A Proteau, R Morona, L Purins, E Ajamian, J Wagner, M Papadopoulos, L Van Den bosch, Bacterial Polysaccharide Co-Polymerases Share a Common Framework for Control of Polymer Length, Nat. Struct. Mol. Biol., 15(2), 130 (2008).[ premier ]
  181. G Buchko, O Litvinova, H Robinson, A Yakunin, M Kennedy, Functional and Structural Characterization of DR_0079 from Deinococcus radiodurans, a Novel Nudix Hydrolase with a Preference for Cytosine (Deoxy)ribonucleoside 5' -Di- and Triphophates, Biochemistry, 47, 6571-6582 (2008).
  182. N Silvaggi, L Martin, H Schwalbe, B Imperiali, K Allen, Double-Lanthanide-Binding Tags for Macromolecular Crystallographic Structure Determination, J. Am. Chem. Soc., 129, 7114-7120 (2007).[ premier ]
  183. H Shin, H Gennadios, D Whittington, D Christianson, Amphipathic Benzoic Acid Derivativies: Synthesis and Binding in the Hydrophobic Tunnel of the Zinc Deacetylase LpxC, BioOrg. Med. Chem., 15(7), 2617-2623 (2007).
  184. Z Zhou, J Zhen, N Karpowich, R Goetz, C Law, M Reith, D Wang, LeuT-Desipramine Structure Reveals How Antidepressants Block Neurotransmitter Reuptake, Science, 317, 1390 (2007).[ premier ]
  185. L Feng, H Yan, Z Wu, N Yan, Z Wang, P Jeffrey, Y Shi, Structure of a Site-2 Protease Family Intramembrane Metalloprotease, Science, 318, 1608-1612 (2007).[ premier ]
  186. W Gordon, D Vardar-Ulu, G Histen, C Sanchez-Irizarry, J Aster, S Blacklow, Structural Basis for Autoinhibition of Notch, Nat. Struct. Mol. Biol., 14(4), 295 (2007).[ premier ]
  187. D Reverter, C Lima, Structural Basis for SENP2 Protease Interactions with SUMO Precursers and Conjugated Substrates, Nat. Struct. Mol. Biol., 13(12), 1060 (2007).[ premier ]
  188. Z Wu, N Yan, L Feng, A Oberstein, H Yan, R Baker, L Gu, P Jeffrey, S Urban, Y Shi, Structrural Analysis of a Rhomboid Family Intramembrane Protease Reveals a Gating Mechanism for Substrate Entry, Nat. Struct. Mol. Biol., 13(12), 1084 (2007).[ premier ]
  189. Y Chen, Y Xu, Q Bao, Y Xing, Z Li, Z Lin, J Stock, P Jeffrey, Y Shi, Structural and Biochemical Insights into the Regulation of Protein Phosphatase 2A by Small t Antigen of SV40, Nat. Struct. Mol. Biol., 14(6), 527 (2007).[ premier ]
  190. P Fitzpatrick, D Bozinovski, A Heroux, P Shaw, M Valley, A Orville, Mechanistic and Structural Analyses of the Roles of Arg409 and Asp402 in the Reaction of the Flavoprotein Nitroalkane Oxidase, Biochemistry, 46, 13800-13808 (2007).
  191. G Patikoglou, L Westblade, E Campbell, V Lamour, W Lane, S Darst, Crystal Structure of the Escherichia coli Regulator of ?70, Rsd, in Complex with ?70 Domain 4, J. Mol. Biol., 372, 649-659 (2007).
  192. J Wang, J Eldo, E Kantrowitz, Structural Model of the R State of Escherichia coli Aspartate Transcarbamoylase with Substrates Bound , J. Mol. Biol., 371(5), 1261-1273 (2007).
  193. J Hoy, H Robinson, J Trent, lll, S Kakar, B Smagghe, M Hargrove, Plant Hemoglobins: A Molecular Fossil Record for the Evolutin of Oxygen Transport, J. Mol. Biol., 371(1), 168-179 (2007).
  194. B Kelly, S Kyere, I Kinde, C Tang, B Howard, H Robinson, W Sundquist, M Summers, C Hill, Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein, J. Mol. Biol., 373(2), 355-366 (2007).
  195. L Lin, Crystal Structure of the Bovine lactadherin C2 Domain, a Membrane Binding Motif, Shows Similarity to the C2 Domains of Factor V and Factor VIII, J. Mol. Biol., 371, 717 (2007).
  196. X He, R van Waardenburg, K Babaoglu, A Price, K Nitiss, J Nitiss, M Bjornsti, S White, Mutation of a Conserved Active Site Residue Converts Tyrosyl-DNA Phosphodiesterase l Into a DNA Topoisomerase l-Dependent Poison, J. Mol. Biol., 372, 1070-1081 (2007).
  197. Y Wang, S Maegawa, Y Akiyama, Y Ha, The Role of L1 Loop in the Mechanism of Rhomboid Intramembrane Protease GlpG, J. Mol. Biol., 374(4), 1104-1113 (2007).
  198. M Stahley, P Adams, J Wang, S Strobel, Structural Metals in the Group I Intron: A Ribozyme with a Multiple Metal Ion Core, J. Mol. Biol., 372(1), 89-102 (2007).
  199. S Oruganti, Y Zhang, H Li, H Robinson, M Terns, R Terns, W Yang, H Li, Alernative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs, J. Mol. Biol., 371(5), 1141-1150 (2007).
  200. H Wang, H Robinson, H Ke, The Molecular Basis for Different Recognition of Substrates by Phosphodiesterase Families 4 and 10, J. Mol. Biol., 371, 302-307 (2007).
  201. S Schroeder, G Blaha, J Tirado-Rives, T Steitz, P Moore, The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole, J. Mol. Biol., 367, 1471-1479 (2007).
  202. A Murkin, M Birck, A Rinaldo-Matthis, W Shi, E Taylor, S Almo, V Schramm, Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase, Biochemistry, 46, 5038-5049 (2007).
  203. R Hall, S Brown, A Fedorov, E Fedorov, C Xu, P Babbitt, S Almo, F Raushel, Structural Diversity Within the Mononuclear and Binuclear Active Sites of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase, Biochemistry, 46, 7953-7962 (2007).
  204. J Lafrance-Vanasse, J Sygusch, Carboxy-Terminus Recruitment Induced by Substrate Binding in Eukaryotic Fructose Bis-phosphate Aldolases, Biochemistry, 46, 9533-9540 (2007).
  205. A Rinaldo-Matthis, C Wing, M Ghanem, H Deng, P Wu, A Gupta, P Tyler, G Evans, R Furneaux, et al., Inhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues, Biochemistry, 46, 659-668 (2007).
  206. E Shishova, L Di Costanzo, D Cane, D Christianson, X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and Evolution of Templates for the Cyclization of Farnesyl Diphosphate, Biochemistry, 46, 1941-1951 (2007).
  207. J Parsons, B Greenhagen, K Shi, K Calabrese, H Robinson, J Ladner, Structural and Functional Analysis of the Pyocyanin Biosynthetic Protein PhzM from Pseudomonas aeruginosa, Biochemistry, 46, 1821-1828 (2007).
  208. E Taylor, A Rinaldo-Matthis, L Li, M Ghanem, K Hazleton, M Cassera, S Almo, V Schramm, Anopheles gambiae Purine Nucleoside Phosphorylase: Catalysis, Structure, and Inhibition, Biochemistry, 46, 12405-12415 (2007).
  209. B Nolen, T Pollard, Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex, Mol. Cell, 26, 449-457 (2007).[ premier ]
  210. M Kvansakul, M van Delft, E Lee, J Gulbis, W Fairlie, D Huang, P Colman, A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak, Mol. Cell, 25(6), 933-942 (2007).[ premier ]
  211. A VanDemark, M Kasten, E Ferris, A Heroux, C Hill, B Cairns, Autoregulation of the Rsc4 Tandem Bromodomain by Gcn5 Acetylation, Mol. Cell, 27(5), 793-805 (2007).[ premier ]
  212. J DiNitto, A Delprato, M Lee, T Cronin, S Huang, A Guilherme, M Czech, D Lambright, Structural Basis and Mechanism of Autoregulation in 3-Phosphoionsitide-Dependent Grp1 Family Arf GTPase Exchange Factors, Mol. Cell, 28(4), 569-583 (2007).[ premier ]
  213. L Deng, R Langley, P Brown, G Xu, L Teng, Q Wang, M Gonzales, G Callender, M Nishimura, et al., Structural Basis for the Recognition of Mutant Self by a Tumor-Specific, MHC Class II-Restricted T Cell Receptor, Nat. Immunol., 8, 398-408 (2007).[ premier ]
  214. S Sunita, E Purta, M Durawa, K Tkaczuk, J Swaathi, J Bujnicki, J Sivaraman, Functional Specialization of Domains Tandemly Duplicated Witin 16S rRNA Methyltransferase RsmC, Nucleic Acids Res., 35, 4264-4274 (2007).[ premier ]
  215. J Khan, S Xiang, L Tong, Crystal Structure of Human Nicotinamide Riboside Kinase, Structure, 15, 1005-1013 (2007).
  216. P Balbo, A Bohm, Mechanism of Poly(A) Polymerase: Structure of the Enzyme-MgATP-RNA Ternary Complex and Kinetic Analysis, Structure, 15, 1117-1131 (2007).
  217. J Carra, C McHugh, S Mulligan, L Machiesky, A Soares, C Millard, Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site, BMC Struct. Biol., 7, 72 (2007).
  218. A Amoia, W Montfort, Apo-Nitrophorin 4 at Atomic Resolution, Protein Sci., 16, 2076-2081 (2007).
  219. S Almo, J Bonanno, J Sauder, S Emtage, T Dilorenzo, V Malashkevich, S Wasserman, S Swaminathan, S Eswaramoorthy, Structural Genomics of Protein Phosphatases, J. Struct. Funct. Genomics, 8(2-3), 121-40 (2007).
  220. C Keiski, P Yip, H Robinson, L Burrows, P Howell, Expression, Purification, Crystallization and Preliminary X-ray Analysis of Pseudomonas fluorescens AlgK, Acta Cryst. F, 63, 415-418 (2007).
  221. X Tang, C Hew, Expression, Purification, Crystallization of Two Major Envelope Proteins from White Spot Syndrome Virus, Acta Cryst. F, 63, 624-626 (2007).
  222. H Wang, Z Yan, J Geng, S Kunz, T Seebeck, H Ke, Crystal Structure of the Leishmania Major Phosphodiesterase LmjPDEB1 and Insight into the Design of hte Parasite-Selective Inhibitors, Mol. Microbiol., 66(4), 1029-1038 (2007).[ premier ]
  223. J Zheng, C He, V Singh, N Martin, Z Jia, Crystal Structure of a Novel Prokaryotic Ser/Thr Kinase and Its Implicatin in the Cpx Stress Response Pathway, Mol. Microbiol., 63(5), 1360-1371 (2007).[ premier ]
  224. G Meinke, P Phelan, S Moine, E Bochkareva, A Bochkarev, P Bullock, A Bohm, The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA., PLoS Biol., 5(2), 0144-0156 (2007).[ premier ]
  225. Z Derewenda, Advances in Protein Crystallography - Fourth Annual Meeting, IDrugs, 10(4), 256-258 (2007).
  226. H Wang, M Peng, Y Chen , J Geng, H Robinson, M Houslay , J Cai, H Ke, Structures of the Four Subfamilies of Phosphodiesterase-4 Provide Insight into the Selectivity of Their Inhibitors, Biochem. J., 408(2), 193-201 (2007).
  227. G Prehna, C Stebbins, A Rac1--GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium, Acta Cryst. D, 63, 628-635 (2007).
  228. O Boudker, R Ryan, D Yernool, K Shimamoto, E Gouaux, Coupling Substrate and Ion Binding to Extracellular Gate of a Sodium-Dependent Aspartate Transporter, Nature, 445, 387-393 (2007).[ premier ]
  229. Q Ye, R Krug, Y Tao, The Mechanism by Which Influenza A Virus Nucleoprotein Forms Oligomers and Binds RNA, Nature, 444, 1078 (2007).[ premier ]
  230. S Singh, A Yamashita, E Gouaux, Antidepressant Binding Site in a Bacterial Homologue of Neurotransmitter Transporters, Nature, 448, 952 (2007).[ premier ]
  231. G Amodeo, M Rudolph, L Tong, Crystal Structure of the Heterotrimer Core of Saccharomyces cerevisiae AMPK Homologue SNF1, Nature, 449, 492 (2007).[ premier ]
  232. J Jasti, H Furukawa, E Gonzales, E Gouaux, Structure of Acid-Sensing Ion Channel 1 at 1.9 angstrom Resolution and Low pH, Nature, 449, 316 (2007).[ premier ]
  233. S Long, X Tao, E Campbell, R MacKinnon, Atomic Structure of a Voltage-Dependent K+ Channel in a Lipid Membrane-Like Environment, Nature, 450, 376 (2007).[ premier ]
  234. B Kelly, Structural Studies of the HIV-1 CA Protein, Ph.D. Thesis. University of Utah, Salt Lake City (2007).
  235. B Manjasetty, W Shi, C Zhan, A Fiser, M Chance, A High-throughput Approach to Protein Structure Analysis, Genetic Engineering : Principles and Methods, p. 105-128, Springer, New York (2007).
  236. C Yun, T Boggon, Y Li, M Woo, H Greulich, M Meyerson, M Eck, Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity, Cancer Cell, 11, 217-227 (2007).[ premier ]
  237. H Demirci, Structure Determination of the T. thermophilus Protein Methyltransferase A in Complex with its Substrate Ribosomal Protein L11, Ph.D. Thesis. Brown University, Providence (2007).
  238. E Cao, X Zang, U Ramagopal, A Mukhopadhaya, A Fedorov, E Fedorov, W Zencheck, J Lary, J Cole, et al., T Cell Immunoglobulin Mucin-3 Crystal Structure Reveals a Galectin-9-Independent Ligand-Binding Surface, Immunity, 26, 311-321 (2007).[ premier ]
  239. C Velikovsky, L Deng, L Chlewicki, M Fernandez, V Kumar, R Mariuzza, Structure of Natural Killer Receptor 2B4 Bound to CD48 Reveals Basis for Heterophilic Recognition in Signaling Lymphocyte Activation Molecule Family, Immunity, 27(4), 572-584 (2007).[ premier ]
  240. J Kavran, S Gundllapalli, P O'Donoghue, M Englert, D Soll, T Steitz, Structure of Pyrrolysyl-tRNA Synthetase, an Archaeal Enzyme for Genetic Code Innovation, Proc Natl Acad Sci USA, 104(27), 11268-11273 (2007).[ premier ]
  241. K Chattopadhyay, U Ramagopal, A Mukhopadhaya, V Malashkevich, T DiLorenzo, M Brenowitz, S Nathenson, S Almo, Assembly and Structural Properties of Gluoccorticoid-Induced TNF Receptor Ligand: Implications for Function, Proc Natl Acad Sci USA, 104(49), 19452-19457 (2007).[ premier ]
  242. E Lew, J Bae, E Rohmann, B Wollnik, J Schlessinger, Structural Basis for Reduced FGFR2 Activity in LADD Syndrome: Implications for FGFR Autoinhibition and Activation, Proc Natl Acad Sci USA, 104(50), 19802-19807 (2007).[ premier ]
  243. W Nguitragool, C Miller, CLC CI-/H+ Transporters Constrained by Covalent Cross-Linking, Proc Natl Acad Sci USA, 104(52), 20659-20665 (2007).[ premier ]
  244. B Welch, A VanDemark, A Heroux, C Hill, M Kay, Potent D-Peptide Inhibitors of HIV-1 Entry, Proc Natl Acad Sci USA, 104(43), 16828-16833 (2007).[ premier ]
  245. X Hu, H Wang, H Ke, B Kuhlman, High-Resolution Design of a Protein Loop, Proc Natl Acad Sci USA, 104(45), 17668-17673 (2007).[ premier ]
  246. Q Yan, V Malashkevich, A Fedorov, E Fedorov, E Cao, J Lary, J Cole, S Nathenson, S Almo, Structure of CD84 Provides Insight into SLAM Family Function, Proc Natl Acad Sci USA, 104(25), 10583-10588 (2007).[ premier ]
  247. S Kamtekar , M Hohn, h Park, M Schnitzbauer, A Sauerwald, D Soll, T Steitz, Toward Understanding Phosphoseryl-tRNA Cys Formation: The Crystal Structure of Methanococcus maripaludis Phosphoseryl-tRNA Synthetase, Proc Natl Acad Sci USA, 104(8), 262-2625 (2007).[ premier ]
  248. H Wang, Y Liu, J Hou, M Zheng, H Robinson, H Ke, Structural Insight into Substrate Specificity of Phosphodiesterase 10, Proc Natl Acad Sci USA, 104(14), 5782-5787 (2007).[ premier ]
  249. P Czabotar, E Lee, M van Delft, C Day, B Smith, D Huang, W Fairlie, M Hinds, P Colman, Structural Insights into the Degradation of Mcl-1 Induced by BH3 Domains, Proc Natl Acad Sci USA, 104(15), 6217-6222 (2007).[ premier ]
  250. J Murphy, Y Cho, A Sachpatzidis, C Fan, M Hodsdon, E Lolis, Structural and Functional Basis of CXCL12 (stromal cell-derived factor-1 alpha) Binding to Heparin, J. Biol. Chem., 282(13), 10018 (2007).
  251. Y Cho, B Jones, J Vermeire, L Leng, L DiFedele, L Harrison, H Xiong, Y Kwong, Y Chen, Structural and Functional Characterization of a Secreted Hookworm Macrophage Migration Inhibitory Factor (MIF) that Interacts with the Human MIF Receptor CD74, J. Biol. Chem., 282(32), 23447 (2007).
  252. P Schelling, K Guglielml, E Kirchner, b Paetzold, T Dermody, T Stehle, The Reovirus Sigmal Aspartic Acid Sandwich: A Trimerization Motif Poised for Conformational Change, J. Biol. Chem., 282, 11582-11589 (2007).
  253. K Hsia, P Stavropoulos, G Blobel, A Hoelz, Architecture of a Coat for the Nuclear Pore Membrane, Cell, 131(7), 1313-1326 (2007).[ premier ]
  254. E Levin, D Kondrashov, G Wesenberg, G Philips, Jr., Ensemble Refinement of Protein Crystal Structures: Validation and Application, Cell, 15, 1040-1052 (2007).[ premier ]
  255. D Lietha, X Cai, D Ceccarelli, Y Lietha, M Schaller, M Eck, Structural Basis for the Autoinhibition of Focal Adhesion Kinase, Cell, 129, 1177-1187 (2007).[ premier ]
  256. T Pfister, A Mirarefi, A Gengenbach, X Zhao, C Danstrom , N Conatser, Y Gao, H Robinson, C Zukoski, et al., Kinetic and Crystallgraphic Studies of a Redesigned Manganese-Binding Site in Cytochrome c Peroxidase, J. Biol. Chem., 12, 126-137 (2007).
  257. S Xu, B Benoff, H Liou, P Lobel, A Stock, Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease, J. Biol. Chem., 282(32), 23525-23531 (2007).
  258. R Fisher, H Chung, Q Zhai, H Robinson, W Sundquist, C Hill, Structural and Biochemical Studies of ALIX/AlP1 and Its Role in Retrovirus Budding, Cell, 128, 841-852 (2007).[ premier ]
  259. L Di Costanzo, M Moulin, M Haertlein, F Meilleur, D Christianson, T , Expression, Purification, Assay, and Crystal Structure of Perdeuterated Human Arginase I , Arch. Biochem. Biophys., 465(1), 82-89 (2007).
  260. M Nishida, M Cadene, B Chait, R MacKinnon, Crystal Structure of a Kir3.1-Prokaryotic Kir Channel Chimera, EMBO J., 26, 4005-4015 (2007).[ premier ]
  261. X Ma, N Sayed, A Beuve, F van den Akker, NO and CO Differentially Activate Soluble Guanylyl Cyclase via a Heme Pivot-bend Mechanism, EMBO J., 26, 578-588 (2007).[ premier ]
  262. P Balbo, J Toth, A Bohm, X-ray Crystallographic and Steady State Fluorescence Characterization of the Protein Dynamics of Yeast Polyadenylate Polymerase., J. Mol. Biol., 366, 1401–1415 (2007).
  263. S Yohannan, Y Hu, Y Zhou, Crystallographic Study of the Tetrabutylammonium Block to the KcsA K+ Channel, J. Mol. Biol., 366(3), 806-814 (2007).
  264. J Jefferson, C Ciatto, l Shapiro, R Liem, Structural Analysis of the Plakin Domain of Bullous Pemphigiod Antigen1 (BPAG1) Suggests That Plakins are Members of the Spectrin Superfamily, J. Mol. Biol., 366(1), 244-257 (2007).
  265. K Baek, R Brown, G Birrane, J Ladias, Crystal Structure of Human Cyclin K, A Positive Regulator of Cyclin-Dependent Kinase 9, J. Mol. Biol., 366(2), 563-573 (2007).
  266. H Wang, M Ye, H Robinson, S Fransis, H Ke, Conformational Variations of Both Phosphodiesterase-5 and Inhibitors Provide the Structural Basis for the Physiological Effects of Vardenafil and Sildenafil, Mol. Pharmacol., 73(1), 104-10 (2007).
  267. Y Liu, Z Li, Q Lin, J Kosinski, J Seetharaman, J Bujnicki, J Sivaraman, C Hew, Structure and Evolutionary Origin of Ca2+-Dependent Herring Type II Antifreeze Protein, PLoS One, 2(6), 548 (2007).
  268. C Jobichen, M Li, G Yerushalmi, Y Tan, Y Mok, I Rosenshine, K Leung, J Sivaraman, Structure of GrlR and the Implication of its EDED Motif in Mediating the Regulation of Type III Secretion System in EHEC, Plos Pathog., 3(5), 69 (2007).
  269. E Rangarajan, G Nadeau, Y Li, J Wagner, M Hung, J Schrag, M Cygler, A Matte, The structure of the exopolyphsophatase (PPX) from Escherchia coli O157:H7 suggests a binding mode for long polyphosphate chains, J. Mol. Biol., 359(5), 1249-1260 (2006).
  270. W Nguitragool, C Miller, Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions, J. Mol. Biol., 362, 682-690 (2006).
  271. B Manjasetty, M Chance, Crystal Structure of Escherichia coli L-Arabinose Isomerase (ECAI), The Putative Target of Biological Tagatose Production, J. Mol. Biol., 360(2), 297-309 (2006).
  272. G Meinke, P Bullock, A Bohm, Crystal Structure of the Simian Virus 40 Large T-Antigen Origin-Binding Domain, J. Virology, 80, 4304 (2006).
  273. H Wang, Y Liu, Q Huai, J Cai, R Zoraghi, S Francis, J Corbin, H Robinson, Z Xin, et al., Multiple Conformations of Phosphodiesterase-5: Implications for Enzyme Function and Drug Developement, J. Biol. Chem., 281, 21469 (2006).
  274. W Hwang, Y Lin, E Santelli, J Sui, L Jaroszewski, B Stec, M Farzan, W Marasco, R Liddington, Structural Basis of Neutralization by a Human Anti-severe Acute Respiratory Syndrome Spike Protein Antibody,80R., J. Biol. Chem., 281, 34610-6 (2006).
  275. D Shaya, A Tocilj, Y Li, J Myette, G Venkatarman, R Sasisekharan, M Cygler, Crystal Structure of Heparinase II from Pedobacter Heparinus and its Complex with a Disaccharide Product, J. Biol. Chem., 281(2), 22 (2006).
  276. I Schoenhofen, V Lunin, J Julien, Y Li, E Ajamian, A Matte, M Cygler, J Brisson, A Aubry, et al., Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter Pylori, J. Biol. Chem., 281(13), 8907-8916 (2006).
  277. Y Xu, Y Xing, Y Chen, Y Chao, Z Lin, E Fan, J Yu, S Strack, P Jeffrey, Y Shi, Structure of the Protein Phosphatase 2A Holoenzyme, Cell, 127, 1239-1251 (2006).[ premier ]
  278. M Suits, N Jaffer, Z Jia, Structure of the Escherichia coli O157:H7 heme oxygenase ChuS in complex with heme and enzymatic inactivation by mutation of the heme coordinating residue His-193, J. Biol. Chem., 281(48), 36776-82 (2006).
  279. E Cao, U Ramagopal, A Fedorov, E Fedorov, Q Yan, J Lary, J Cole, S Nathenson, S Almo, NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family, Immunity, 25, 559-570 (2006).[ premier ]
  280. H Zhu, J Nandakumar, J Aniukwu, L Wang, M Glickman, C Lima, S Shuman, Atomic Structure and Nonhomologous End-Joining Function of the Polymerase Component of Bacterial DNA Ligase D, Proc Natl Acad Sci USA, 103(6), 1711-1716 (2006).[ premier ]
  281. L Esser, X Gong, S Yang, L Yu, C Yu, D Xia, Surface-Modulated Motion Switch: Capture and Release of Iron-Sulfur Protein in the Cytochrome bc1 Complex, Proc Natl Acad Sci USA, 103, 13045-13050 (2006).[ premier ]
  282. E Schreiter, S Wang, D Zamble, C Drennan, NikR-Operator Complex Structure and the Mechanism of Repressor Activation by Metal Ions, Proc Natl Acad Sci USA, 103(37), 13676-13681 (2006).[ premier ]
  283. B Manjasetty, A Turnbull, K Bussow, M Chance, Recent Advances in Protein Structure Analysis , Recent Research Developments in Biochemistry, p. 47-71, Transworld Research Network, Trivandrum (2006).
  284. E Enemark, L Joshua-Tor, Mechanism of DNA Translocation in a Replicative Hexameric Helicase, Nature, 442, 270-275 (2006).[ premier ]
  285. I Lorenz, J Marcotrigiano, T Dentzer, C Rice, Structure of the catalytic domain of the hepatitis C virus NS2-3 protease, Nature, 442(7104), 831-5 (2006).[ premier ]
  286. X Pan, S Eathiraj, D Lambright, TBC-Domain GAPs for Rab GTPases Accelerate GTP Hydrolysis by a Dual-Finger Mechanism, Nature, 442, 303-306 (2006).[ premier ]
  287. Y Nam, P Silz, L Song, J Aster, S Blacklow, Structural Basis for Cooperativity in Recruitment of MAML Co-activators to Notch Transcription Complexes, Cell, 124, 973-983 (2006).[ premier ]
  288. G Prehna, M Ivanov, J Blisha, C Stebbins, Yersinia Virulence Depends on Mimicry of Host Rho-Family Nucleotide Dissociation Inhibitors, Cell, 126, 869-880 (2006).[ premier ]
  289. J Nandakumar, S Shuman, C Lima, RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward, Cell, 127(1), 71-84 (2006).[ premier ]
  290. G Hu, G Lin, M Wang, L Dick, R Xu, C Nathan, H Li, Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate, Mol. Microbiol., 59(5), 1417-1428 (2006).[ premier ]
  291. G Buchko, H Robinson, S Ni, H Pakrasi, M Kennedy, Cloning, Expression, Crystallization and Preliminary Crystallographic Analysis of a Pentapeptide-repeat Protein (Rfr23) from the Bacterium Cyanothece 51142l, Acta Cryst. F, F62, 1251-1254 (2006).
  292. S Fisher, L Govindasamy, N Boyle, M Agbandje-McKenna, D Silverman, G Blackburn, R McKenna, X-ray Crystallographic Studies Reveal That the Incorporation of Spacer Groups in Carbonic Anhydrase Inhibitors Causes Alternate Binding Modes, Acta Cryst. F, 62, 618 (2006).
  293. M Safo, T Ko, F Musayev, Q Zhao, A Wang, G Archer, Structure of the Mecl Repressor from Staphylococcus aureus in Complex with the Cognate DNA Operator of mec, Acta Cryst. F, 62, 320-324 (2006).
  294. H Gill, W Boron, Preliminary X-ray Diffraction Analysis of the Cytoplasmic N-terminal Domain of the Na/HCO3 Cotransporter NBCe1-A, Acta Cryst. F, 62, 534-537 (2006).
  295. Y Leduc, C Phenix, J Puttick, K Nienaber, D Palmer, L Delbaere, Crystallization, Preliminary X-ray Diffraction and Structure Solution of MosA, a Dihydrodipicolinate Synthase from Sinorhizobium Meliloti L5-30, Acta Cryst. F, F62, 49-51 (2006).
  296. S Margarit, W Davidson, L Frego, F Stebbins, A Steric Antagonism of Actin Polymerization by a Salmonella Virulence Protein, Structure, 14, 1219-1229 (2006).
  297. Y Yuan, Y Pei, H Chen, T Tuschl, D Patel, A Potential Protein-RNA Recognition Event Along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA, Structure, 14(10), 1557-1565 (2006).
  298. H Gill, W Boron, Expression and Purification of the Cytoplasmic N-Terminal Domain of the Na/HCO3 Cotransporter NBCe1-A: Structural Insights from the a Generalized Approach, Protein Expr. Purif., 49(2), 228-234 (2006).
  299. G Buchko, S Ni, H Robinson, E Welsh, H Pakrasi, M Kennedy, Characterization of two Potentially Universal Turn Motifs that Shape the Repeated VFive-Residues Fold - Crystal Structure of a Lumenal Pentapeptide Repeat Protein from Cyanothece 51142, Protein Sci., 15, 2579-2595 (2006).
  300. Y Shen, C Chou, G Chang, L Tong, Is Dimerization Required for the Catalytic Activity of Bacterial Biotin Carboxylase?, Mol. Cell, 22, 807 (2006).[ premier ]
  301. Y Chao, Y Xing, Y Chen, Y Xu, Z Lin, Z Li, P Jeffrey, J Stock, Y Shi, Structure and Mechanism of the Phosphotyrosyl Phosphatase Activator, Mol. Cell, 23, 535-546 (2006).[ premier ]
  302. C Fisher, N Beglova, s Blacklow, Structure of an LDLR-RAP Complex Reveals a General Mode for Ligand Recognition by Lipoprotein Receptors , Mol. Cell, 22, 277-283 (2006).[ premier ]
  303. D Copeland, A Soares, A West, G Richter-Addo, Crystal Structures of the Nitrite and Nitric Oxide Complexes of Horse Heart Myoglobin, J. Inorg. Biochem., 100(8), 1413-1425 (2006).
  304. M Lilic, M Vujanac, C Stebbins, A Common Structural Motif in the binding of Virulence Factors to Bacterial Secretion Chaperones, Mol. Cell, 21, 653-664 (2006).[ premier ]
  305. P Sanghani, W Davis, L Zhai, H Robinson, Structure-Function Relationships in Human Glutathione-Dependent Formaldehyde Dehydrogenase. Role of Glu-67 and Arg-368 in the Catalytic Mechanism, Biochemistry, 45, 4819-4830 (2006).
  306. J Kim, V Malashkevich, S Roday, M Lisbin, V Schramm, S Almo, Structural and Kinetic Characterization of Escherichia coli TadA, the Wobble-Specific tRNA Deaminase, Biochemistry, 45, 6407-6416 (2006).
  307. W Shi, H Robinson, M Sullivan, D Abel, J Toomey, L Berman, D Lynch, G Rosenbaum, G Rakowsky, et al., Beamline X29: A Novel Undulator Source for X-ray Crystallography, J. Synch. Rad., 13, 365-372 (2006).
  308. J Lu, D Ho, N Vogelaar, C Kraml, S Bernhard, N Byme, L Kim, R Pascal, Jr., Synthesis, Structure, and Resolution of Exceptionally Twisted Pentacenes, J. Am. Chem. Soc., 128, 17043-17050 (2006).[ premier ]
  309. P Pawelek, N Croteau, C Ng-Thow-Hing, C Khursigara, N Moiseeva, M Allaire, J Coulton, Structure of TonB in Complex with FhuA, E. Coli Outer Membrane Receptor, Science, 312, 1399-1402 (2006). [76801][ premier ]
  310. W Yew, A Fedorov, E Fedorov, J Rakus, R Pierce, S Almo, J Gerlt, Evolution of Enzymatic Activities in the Enolase Superfamily: L-Fuconate Dehydratase from Xanthomonas campestris, Biochemistry, 45, 14582-14597 (2006).
  311. B Kelly, B Howard, H Wang, H Robinson, W Sundquist, C Hill, Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag1-278 and CAN133-278, Biochemistry, 45(38), 11257 -11266 (2006).
  312. C Johnston, E Lobanova, A Shavkunov, J Low, J Ramer, R Blasesius, Z Fredericks, F willard, B Kuhlman, et al., Minimal Determinants for Binding Activated G alpha from the Structure of a G alpha i1-Peptide Dimer, Biochemistry, 45, 11390-11400 (2006).
  313. J Cordero-Morales, L Cuello, Y Zhao, V Jogini, D Cortes, B Roux, E Perozo, Molecular Determinants of Gating at the Potassium-Channel Selectivity Filter, Nat. Struct. Mol. Biol., 13(4), 311 (2006).[ premier ]
  314. W Barton, D Tzvetkova-Robev, E Miranda, M Kolev, K Rajashankar, J Himanen, D Nikolov, Crystal Structures of the Tie2 Receptor Ectodomain and the Angiopoietin-2–Tie2 Complex, Nat. Struct. Mol. Biol., 13, 524-532 (2006).[ premier ]
  315. S Mylavarapu, M Furgason, D Brewer, M Munson, The Structure of the Exocyst Subunit Sec6p Defines a Conserved Architecture with Diverse Roles, Nat. Struct. Mol. Biol., 13(6), 555-556 (2006).[ premier ]
  316. D Nair, R Johnson, L Prakash, S Prakash, A Aggarwal, Hoogsteen Base Pair Formation Promotes Synthesis Opposite the 1, N6-Ethenodeoxyadenosine Lesion by Human DNA Polymerase 1, Nat. Struct. Mol. Biol., 13(7), 619 (2006).[ premier ]
  317. A Ruthenburg, W Wang, D Graybosch, H Li, D Allis, D Patel, G Verdine, Histone H3 Recogntion and Presentation by the WDR5 Module of the MLL1 Complex, Nat. Struct. Mol. Biol., 13(8), 704 (2006).[ premier ]
  318. S Alam, C Langelier, F Whitby, S Koirala, H Robinson, C Hill, W Sundquist, Structural Basis for Ubiquitin Recognition by the Human ESCRT-II EAP45 GLUE Domain, Nat. Struct. Mol. Biol., 13(11), 1029-1030 (2006).[ premier ]
  319. G Dong, A Hutagalung, C Fu, P Novick, K Reinisch, The Structures of Exocyst Subunit Exo70p and the Exo84p C-terminal Domains Reveal a Common Motif, Nat. Struct. Mol. Biol., 12(12), 1094 (2005).[ premier ]
  320. S Long, E Campbell, R MacKinnon, Voltage Sensor of Kv1.2: Structural Basis of Electromechanical Coupling, Science, 309, 903 (2005).[ premier ]
  321. S Long, E Campbell, R MacKinnon, Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K+ Channel, Science, 309, 897 (2005).[ premier ]
  322. R Agarwal, T Binz, S Swaminathan, Structural Analysis of Botulinum Neurotoxin Serotype F Light Chain: Implications on Substrate Binding and Inhibitor Design, Biochemistry, 44, 11758-11765 (2005).
  323. I Mirza, I Nazi, M Korczynska, G Wright, A Berghuis, Crystal Structure of Homoserine Transacetylase from Haemophilus Influenzae Reveals a New Family of alpha/beta-Hydrolases, Biochemistry, 44, 15768-15773 (2005).
  324. M Hahn, M Nicholson, J Pyrdol, K Wucherpfennig, Unconventional Topology of Self Peptide-Major Histocompatibility Complex Binding by a Human Autoimmune T Cell Receptor, Nat. Immunol., 6, 490-496 (2005).[ premier ]
  325. J Gorman, L Shapiro, Crystal Structures of the Tryptophan Repressor binding Protein WrbA and complexes with Flavin Mononucleotide, Protein Sci., 14, 3004-3012 (2005).
  326. M DiMattia, L Govindasamy, H Levy, B Whitaker-Gurda, E Kohlbrenner, J Chiorini, R McKenna, N Muzyczka, S Zolotukhin, M Agbandje-McKenna, Production, Purification, Crystallization and Preliminary X-ray Structural Studies of Adeno-Associated Virus Serotype 5, Acta Cryst. F, F61, 917-921 (2005).
  327. C Zhan, E Fedorov, W Shi, U Ramagopal, R Thirumuruhan, B Manjasetty, S Almo, A Fiser, M Chance, A Fedorov, The ybeY Protein from Escherichia coli is a Metalloprotein, Acta Cryst. F, 61(11), 959-963 (2005).
  328. E Bitto, C Bingman, H Robinson, S Allard, G Wesenberg, G Phillips, Jr., The Crystal Structure at 2.5 Angstrom Resolution of Human Basophilic Leukemia-Expressed Protein BLES03, Acta Cryst. F, 61, 812 (2005).
  329. J Bonanno, S Almo, A Bresnick, M Chance, A Fiser, S Swaminathan, J Jiang, F Studier, L Shapiro, New York-Structural GenomiX Research Consortium (NYXGXRC): a Large Scale Center for the Protein Structure Initiative, J. Struct. Funct. Genomics, 6, 225-32 (2005).
  330. A Forster, E Masters, F Whitby, H Robinson, C Hill, The 1.9 Angstrom Structure of a Proteasome-11S Activator Complex and Implications for the Proteasome-Pan/PA700 Interactions, Mol. Cell. Bio., 18, 589 (2005).[ premier ]
  331. Y Im, S Raychaudhuri, W Prinz, J Hurley, Structural Mechanism for Sterol Sensing and Transport by OSBP-Related Proteins, Nature, 437, 154-158 (2005).[ premier ]
  332. J Wang, K Stieglitz, J Cardia, E Kantrowitz, Structural Basis for Ordered Substrate Binding and Cooperativity in Aspartate Transcarbamoylase, Proc Natl Acad Sci USA, 102, 8881-8886 (2005).[ premier ]
  333. M Nicholson, M Hahn, K Wucherpfennig, Unusual features of Self-Peptide/MHC Binding by Autoimmune T Cell Receptors, Immunity, 23(4), 351-360 (2005).[ premier ]
  334. J Brown, Z Zhou, L Reshetnikova, H Robinson, R Yammani, L Tobacman, C Cohen, Structure of the Mid-Region Tropomyosin: Bending and Binding Sites for Actin, Proc Natl Acad Sci USA, 102(52), 18878-18883 (2005).[ premier ]
  335. E Rangarajan, Y Li, E Ajamian, P Iannuzzi, S Kernaghan, M Fraser, M Cygler, A Matte, Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases, J. Biol. Chem., 280(52), 42919-42928 (2005).
  336. H Wang, Y Liu, Y Chen, H Robinson, H Ke, Multiple Elements Jointly Determine Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases 4 and 7, J. Biol. Chem., 280, 30949 (2005).
  337. L Deng, C Velikovsky, C Swaminathan , S Cho, R Mariuzza, Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase CGAMMA1, J. Mol. Biol., 352, 1 (2005).
  338. D Nesic, Y Hsu, C Stebbins, Assembly and function of a bacterial genotoxin, Nature, 429, 429-433 (2004).[ premier ]
  339. J Lu, D Ho, N Vogelaar, C Kraml, R Pascal, Jr., A Pentacene with a 144 degree Twist, J. Am. Chem. Soc., 126, 11168-11169 (2004).[ premier ]

[ premier ] - A publication is considered premier if the journal has an impact factor of 6 or greater (from Journal Citation Report 2003, Thomson Institute for Scientific Information). These journals represent approximately the top 3% of all journals. Two additional journals are included in the NSLS premier list, Applied Physics Letters (impact factor 4.0) and Environmental Sciences and Technology (impact factor 3.6), because these journals represent the "best in class" for the NSLS industrial and environmental science users, even though their impact factors are less than 6.