X9A Publications

1. Z Cai, N Chehab, N Pavletich, Structure and Activation Mechanism of the CHK2 DNA Damage Checkpoint Kinase, Cell, 35(6), 818-829 (2009).[ premier ]
2. J Himanen, Y Goldgur, H Miao, E Myshkin, H Guo, M Buck, M Nguyen, K Rajashankar, B Wang, D Nikolov, Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex, EMBO J., 10(7), 722-728 (2009).[ premier ]
3. H Li, M Motamedi, C Yip, Z Wang, T Walz, D Patel, D Moazed, An Alpha Motif at Tas3C Terminus Mediates RITS Cis Spreading and Promotes Heterochromatic Gene Silencing, Mol. Cell, 34, 155-167 (2009).[ premier ]
4. J Mancias, J Goldberg, Structural Basis of Cargo Membrane Protein Discrimination by the Human COPll Coat Machinery, EMBO J., 27, 2918 (2008).[ premier ]
5. S Hirota, T Kawahara, M Beltramini, P Di Muro, R Magliozzo, J Peisach, L Powers, N Tanaka, S Nagao, L Bubacco, Molecular Basis of the Bohr Effect in Arthropod Hemocyanin, J. Biol. Chem., 283, 31941-31948 (2008).
6. K Hsia, P Stavropoulos, G Blobel, A Hoelz, Architecture of a Coat for the Nuclear Pore Membrane, Cell, 131(7), 1313-1326 (2007).[ premier ]
7. A Bagaria, K Surendranath, U Ramagopal, S Ramakumar, A Karande, Structure-Function Analysis and Insights into the Reduced Toxicity of Abrus Precatoriu Agglutinin I in Relation to Abrin, J. Biol. Chem., 281, 34465-34474 (2007).
8. H Zhu, P Smith, L Wang, S Shuman, Structure-Function Analysis of the 3' Phosphatase Component of T4 Polynucleotide Kinase/phosphatase, J. Virology, 366(1), 126-136 (2007).
9. Q Yan, V Malashkevich, A Fedorov, E Fedorov, E Cao, J Lary, J Cole, S Nathenson, S Almo, Structure of CD84 Provides Insight into SLAM Family Function, Proc Natl Acad Sci USA, 104(25), 10583-10588 (2007).[ premier ]
10. J Napetschnig, G Blobel, A Hoelz, Crystal Structure of the N-Terminal Domain of the Human Protooncogene Nup214/CAN, Proc Natl Acad Sci USA, 104(6), 1783-1788 (2007).[ premier ]
11. S Klinke, V Zylberman, H Bonomi, I Haase, B Guimaraes, B Braden, A Bacher, M Fischer, F Goldbaum, Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales, J. Mol. Biol., 373, 664-680 (2007).
12. H Imker, A Fedorov, E Fedorov, S Almo, J Gerlt, Mechanistic Diversity in the RuBisCO Superfamily: The "Enolase" in the Methionine , Biochemistry, 46, 4077-4089 (2007).
13. M Dellarole, I Sanchez, E Freire, G de Prat-Gay, Increased Stability and DNA Site Discrimination of "Single Chain" Variants of the Dimeric beta-Barrel DNA Binding Domain of the Human Papillomavirus E2 Transcriptional Regulator, Biochemistry, 46, 12441-12450 (2007).
14. P Nair, J Nandakumar, P Smith, M Odell, C Lima, S Shuman, Structural Basis for Nick Recognition by a Minimal Pluripotent DNA Ligase, Nat. Struct. Mol. Biol., 14(8), 770 (2007).[ premier ]
15. J Mancias, J Goldberg, The Transport Signal on Sec22 for Packaging into COPII-Coated Vesicles is a Conformational Epitope, Mol. Cell, 26(3), 403-414 (2007).[ premier ]
16. B Hao, S Oehlmann, M Sowa, J Harper, N Pavletich, Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases, Mol. Cell, 26(1), 131-143 (2007).[ premier ]
17. E Campbell, R Greenwell, J Anthony, S Wang, L Lim, K Das, H Sofia, T Donohue, S Darst, A Conserved Structural Module Regulates Transcriptional Responses to Diverse Stress Signals in Eubacteria, Mol. Cell, 27, 793-805 (2007).[ premier ]
18. L Olsen, M Vetting, S Roderick, Structure of the E. Coli Bifunctional GlmU Acetyltransferase Active Site with Substrates and Products, Protein Sci., 16, 1230-1235 (2007).
19. I Melcak, A Hoelz, G Blobel, Structure of Nup58/45 Suggests Flexible Nuclear Pore Diameter by Intermolecular Sliding, Science, 315, 1729 (2007).[ premier ]
20. P Velge, M Herler, J Johansson, S Roches, S Temoin, A Fedorov, P Gracieux, S Almo, W Goebel, P Cossart, A Naturally Occurring Mutation K220T in the Pleiotropic Activator PrfA of Listeria Monocytogenes Results in a Loss of Virulence Due to Decreasing DNA-Binding Affinity, Microbiology, 153, 995-1005 (2007).
21. T Hermann, V Tereshko, E Skripkin, D Patel, Apramycin Recognition by the Human Ribosomal Decoding Site, Blood Cell. Mol. Dis., 38(3), 193-198 (2007).
22. Y Leduc, C Phenix, J Puttick, K Nienaber, D Palmer, L Delbaere, Crystallization, Preliminary X-ray Diffraction and Structure Solution of MosA, a Dihydrodipicolinate Synthase from Sinorhizobium Meliloti L5-30, Acta Cryst. F, F62, 49-51 (2006).
23. S Margarit, W Davidson, L Frego, F Stebbins, A Steric Antagonism of Actin Polymerization by a Salmonella Virulence Protein, Structure, 14, 1219-1229 (2006).
24. M Roden, D Brims, A Fedorov, T DiLorenzo, S Almo, s Nathenson, L Anovitz, D Wesolowski, Structural Analysis of H2-Db Class I Molecules Containing Two Different Allelic Forms of the type 1 Diabetes Susceptibility Factor beta-2 Microglobulin: Implications for the Mechanism Underlying Viriations in Antigen Presentation, Mol. Immunol., 43(9), 1370-1378 (2006).
25. M Lilic, M Vujanac, C Stebbins , A Common Structural Motif in the Binding of Virulence Factors to Bacterial Secretion Chaperones, Mol. Cell, 21, 653-664 (2006).[ premier ]
26. B Manjasetty, K Bussow, M Fieber-ErdMan, Y Roske, J Gobam, C Scheich, F Gotz, F Niesen, U Heinemann, Crystal Structure of Homo Sapiens PTD012 Reveals a Zinc-Containing Hydrolase Fold, Protein Sci., 15, 914-920 (2006).
27. M Vetting, S Hegde, J Fajardo, A Fiser, S Roderick, H Takiff, J Blanchard, The Pentapeptide Repeat Proteins, Biochemistry, 45, 1-10 (2006).
28. W Yew, A Fedorov, E Fedorov, J Rakus, R Pierce, S Almo, J Gerlt, Evolution of Enzymatic Activities in the Enolase Superfamily: L-Fuconate Dehydratase from Xanthomonas campestris, Biochemistry, 45, 14582-14597 (2006).
29. W Yew, A Fedorov, E Fedorov, B Wood, S Almo, J Gerlt, Evolution of Enzymatic Activities in the Enolase Superfamily: D-Tartrate Dehydratase from Bradyrhizobium japonicum, Biochemistry, 45, 14598-14608 (2006).
30. V Singh, W Shi, S Almo, G Evans, R Furneaux, P Tyler, G Painter, D Lenz, S Mee, et al., Structure and Inhibition of Quorum Sensing Target from Streptococcus pneumoniae, Biochemistry, 45, 12929-12941 (2006).
31. A Ketkar, A Shenoy, U Ramagopal, S Visweswariah, K Suguna, A Structural Basis for the Role of Nucleotide Specifying Residues in Regulating the Oligomerization of the RV1625C Adenylyl Cyclase from M. Tuberculosis, J. Mol. Biol., 356, 904 (2006).
32. V Lamour, B Hogan, D Erie, S Darst, Crystal Structure of Thermus Aquaticus Gfh1, a Gre-factor Paralog that Inhibits rather than Stimulates transcript Cleavage, J. Mol. Biol., 356, 179-188 (2006).
33. A Hoelz, J Janz, S Lawrie, B Corwin, A Lee, T Sakmar, Crystal Structure of the SH3 Domain of beta PIX in Complex with a High Affinity Peptide from PAK2, J. Mol. Biol., 358(2), 509-522 (2006).
34. E McManus, B Luisi, R Perham, Structure of a Putative Lipoate Protein Ligase from Thermoplasma acidophilum and the Mechanism of Target Selection for Post-Translational Modification, J. Mol. Biol., 356(3), 625-637 (2006).
35. B Manjasetty, M Chance, Crystal Structure of Escherichia coli L-Arabinose Isomerase (ECAI), The Putative Target of Biological Tagatose Production, J. Mol. Biol., 360(2), 297-309 (2006).
36. T Schwartz, D Schmidt, S Brohawn, G Blobel, Homodimerization of the G Protein Srbeta in the Nucleotide-Free State Involves Proline cis/trans Isomerication in the Switch II Region, Proc Natl Acad Sci USA, 103(18), 6823-6828 (2006).[ premier ]
37. I Lorenz, J Marcotrigiano, T Dentzer, C Rice, Structure of the catalytic domain of the hepatitis C virus NS2-3 protease, Nature, 442(7104), 831-5 (2006).[ premier ]
38. X Wang, Y Shen, T Watanabe, J Murphy, J Rose, T Tsang, The First Lasing of 193 NM SASE, 4TH Harmonic HGHG and ESASE at the NSLS SDL, FEL 2006, p. 18, sponsored by BESSY (2006).
39. S Patel, C Ciatto, C Chen, F Bahna, M Rajebhosale, N Arkus, I Schieren, S Price, L Shapiro, et al., Type II Cadherin Ectodomain Structures: Implications for Classical Cadherin Specificity, Cell, 124(6), 1255-1268 (2006).[ premier ]
40. G Prehna, M Ivanov, J Blisha, C Stebbins, Yersinia Virulence Depends on Mimicry of Host Rho-Family Nucleotide Dissociation Inhibitors, Cell, 126, 869-880 (2006).[ premier ]
41. T Huber, T Sakmar, The Photoreceptor Membrane as a Model System in the Study of Biological Signal Transduction, Advances in Planar Lipid Bilayers and Liposomes, Elsevier, Oxford (2005).
42. S Li, K Schmitz, P Jeffrey, J Wiltzius, P Kussie, K Ferguson, Structural Basis for Inhibition of the Epidermal Growth Factor Receptor by Cetuximab, Cancer Cell, 7(4), 301-311 (2005).[ premier ]
43. I Berke, Nuts and Bolts of the NPC: The Structure of Nup133, Ph.D. Thesis. Rockefeller University, New York (2005).
44. T Ball, W Edstrom, L Mauch, J Schmitt, B Leistler, H Fiebig, W Sperr, A Hauswirth, P Valent, Gain of Structure and IgE Epitopes by Eukaryotic Expression of the Major Timothy Grass Pollen Allergen, Phl p. 1, FEBS J., 272, 217 (2005).
45. T Tellinghuisen, J Marcotrigiano, C Rice, Structure of the Zinc-Binding Domain of an Essential Component of the Hepatitis C Virus Replicase, Nature, 435, 374 (2005).[ premier ]
46. H Yang, Q Li, J Fan, W Hollomon, N Pavletich, The BRCA2 Homologue Brh2 Nucleates RAD51 Filament Formation at a dsDNA-ssDNA Junction, Nature, 433, 653-657 (2005).[ premier ]
47. L Patskovska, Y Patskovsky, S Almo, R Hirsch, COHbC and COHbS Crystallize in the R2 Quaternary State at Neutral pH in the Presence of PEG 4000 , Acta Cryst. D, 61, 566 (2005).
48. U Ramagopal, Z Dauter, R Thirumuruhan, E Fedorov, S Almo, Radiation-Induced Site-Specific Damage of Mercury Derivatives: Phasing and Implications, Acta Cryst. D, 61(9), 1289-1298 (2005).
49. M Chlenov, Y Masuda, K Murakami, V Nikiforov, S Darst, A Mustaev, Structure and Function of Lineage-Specific Sequence Insertions in the Bacterial RNA Polymerase beta' Subunit, J. Mol. Biol., 353, 138-154 (2005).
50. N Thoma, B Czyzewski, A Alexeev, A Mazin, N Pavletich, Structure of the SW12/SNF2 Chromatin-Remodeling Domain of Eukaryotic Rad54, Nat. Struct. Mol. Biol., 12, 350-356 (2005).[ premier ]
51. J Sun, W Wang, H Yang, S Liu, F Liang, A Fedorov, S Almo, Z Zhang, Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion, Biochemistry, 44, 12009-12021 (2005).
52. D Nikolov, C Li, W Barton, J Himanen, Crystal Structure of the Ephrin-B1 Ectodomain: Implications for Receptor Recognitin and Signaling, Biochemistry, 44, 10947-10953 (2005).
53. E Sickmier, D Brekasis, S Paranawithana, J Bonanno, M Paget, S Burley, C Kielkopf, X-ray Structure of a Rex-Family Repressor/NADH Complex Insights into the Mechanism of Redox Sensing, Structure, 13, 43-54 (2005).
54. W Barton, D Tzvekova, D Nikolov, Structure of the Angiopoietin-2 Receptor Binding Domain and Identification of Surfaces Involved in Tie2 Recognition, Structure, 13(5), 825-832 (2005).
55. D Jian, y Kim, K Maxwell, S Beasley, R Zhang, g Gussin, A Edwards, S Darst, Crystal Structure of Bacteriophage lamda cII and its DNA Complex, Mol. Cell, 19, 259-269 (2005).[ premier ]
56. B Hao, N Zheng, B Schulman, G Wu, J Miller, M Pagano, N Pavletich, Structural Basis of the Cks1-Dependent Recognition of P27Kip1 by the SCF skp2 Ubiquitin Ligase, Mol. Cell, 20(1), 9-19 (2005).[ premier ]
57. N Marinkovic, S Gupta, C Zhan, M Chance, Synchrotron Radiation in Biosciences, Nucl. Instrum. Meth. B, 241(1-4), 242-246 (2005).
58. S Hegde, M Vetting, S Roderick, L Mitchenall, A Maxell, H Takiff, J Blanchard, A Fluoroquinolone Resistance Protein from Mycobacterium tuberculosis That Mimics DNA, Science, 308, 1480 (2005).[ premier ]
59. R Janjusevic, R Abramovitch, G Martin, C Stebbins, A Bacterial Inhibitor of Host Programmed Cell Death Defenses is an E3 Ubiquitin Ligase, Science, 311, 222-226 (2005).[ premier ]
60. A Castell, P Johansson, T Unge, T Jones, K Backbro, Rv0216, a Conserved Hypothetical Protein from Myocbacterium Tuberculosis that is Essential for Bacterial Survival During Infection, has a Double Hotdog Fold, Protein Sci., 14, 1850-62 (2005).
61. B Manjasetty, F Niesen, C Scheich, Y Roske, F Goetz, J Behlke, V Sievert, U Heinemann, K Buessow, X-ray Structure of Engineered Human Aortic Preferentially Expressed Protein-1 (APEG-1), BMC Struct. Biol., 5, 21 (2005).
62. O Quintero-Monzon, A Rodal, B Strokopytov, S Almo, B Goode, Structural and Functional Dissection of the Abp1 ADFH Actin-binding Domain Reveals Versatile In Vivo Adapter Functions, Mol. Biol. Cell., 16, 3128-39 (2005).[ premier ]
63. J Himanen, M Chumley, M Lackmann, C Li, W Barton, P Jeffrey, C Vearing, D Geleick, D Feldheim, et al., Repelling Class Discrimination: EphrinA5 Binds to and Activates EphB2 Receptor Signaling, Nat. Neurosci., 7, 501-509 (2004).[ premier ]
64. J Thorson, W Barton, D Hoffmeister, C Albermann, D Nikolov, Structure-Based Enzyme Engineering and Its Impact on In Vito Glycorandomization, ChemBioChem, 5, 16-25 (2004).
65. P Iyer, S Lawrence, K Luther, K Rajashankar, H Yennawar, J Ferry, H Schindelin, Crystal Structure of Phosphotransacetylase from the Methanogenic Archaeon Methanosarcina thermophilia, Structure, 12, 559-567 (2004).
66. S Rudresh, S Ramakumar, U Ramagopal, Y Inai, S Goel, D Sahal, V Chauhan, De Novo Design and Characterization of a Helical Hairpin Eicosapeptide: Emergence of an Anion Receptor in the Linker Region, Structure, 12, 389-396 (2004).
67. Y Huyen, P Jeffrey, W Derry, J Rothman, N Pavletich, E Stavridi, T Halazonetis, Structural Differences in the DNA Binding Domains of Human p53 and its C. Elegans Ortholog Cep-1, Structure, 12, 1237-1243 (2004).
68. M Klein, W Shi, U Ramagopal, Y Tseng, D Wirtz, D Kovar, C Staiger, S Almo, Structure of the Actin Crosslinking Core of Fimbrin, Structure, 12, 999 (2004).
69. D Jain, B Nickels, L Sun, A Hochschild, S Darst, Structure of a Ternary Transcription Activation Complex, Mol. Cell, 13, 45-53 (2004).[ premier ]
70. L Olsen, B Huang, M Vetting, S Roderick, Structure of Serine Acetyltransferase in Complexes with CoA and Its Cysteine Feedback Inhibitor, Biochemistry, 43, 6013-6019 (2004).
71. A Lesner, A Kartvelishvili, J Lesniak, D Nikolov, M Kartvelishvili, G Trillo-Pazos, E Zablotna, M Simm, Monoubiquitinated Histone H1B is Required for Antiviral Protection in CD4(+)T Cells Resistant to HIV-1, Biochemistry, 43, 16203-16211 (2004).
72. J Lewis, I Szundi, M Kazmi, T Sakmar, D Kliger, Time-Resolved Photointermediate Changes in Rhodopsin Glu 181 Mutants, Biochemistry, 43, 12614-12621 (2004).
73. E Yan, Z Ganim, M Kazmi, B Chang, T Sakmar, R Mathies, Resonance Raman Analysis of the Mechanism of Energy Storage and Chromophore Distortion in the Primary Visual Photoproduct , Biochemistry, 43, 10867-10876 (2004).
74. R Deo, E Schmidt, A Elhabazi, H Togashi, S Burley, S Strittmatter, Structural Bases for CRMP Function in Plexin-dependent Semaphorin3A Signaling, EMBO J., 23, 9-22 (2004). [ ][ premier ]
75. A Bobkov, A Muhlrad, A Shvetsov, S Benchaar, D Scoville, S Almo, E Reisler, Cofilin (ADF) Affects Lateral Contacts in F-Actin , J. Mol. Biol., 337, 93-104 (2004).
76. S Masuda, K Murakami, S Wang, C Olson, J Donigian, F Leon, S Darst, E Campbell, Crystal structures of the ADP and ATP bound forms of the Bacillus anti-ssigma factor SpoIIAB in complex with the anti-anti-sigma SpoIIAA, J. Mol. Biol., 340, 941-956 (2004).
77. A Gogos, J Gorman, L Shapiro, Structure of Escherichia coli YfdW, a type lll CoA Transferase, Acta Cryst. D, 60, 507-511 (2004).
78. L Jacquamet, J Ohana, J Joly, P Legrand, R Kahn, F Borel, M Pirocchi, P Charrault, J Ferrer, A New Highly Integrated Sample Environment for Protein Crystallography, Acta Cryst. D, 60, 888-894 (2004).
79. K Sekar, V Rajakannan, D Velmurugan, T Yamane, R Thirumurugan, M Dauter, Z Dauter, A Redetermnation of the Structure of the Triple Mutant (K53,56,120M) of Phosphiolipase A2 at 1.6 A Resolution using Sulfur-SAS at 1.54 A Wavelength, Acta Cryst. D, 60(9), 1586-1590 (2004).
80. R Misra, H Xiao, K Kim, S Lu, W Han, S Barbosa, J Hunt, D Rawlins, W Shan, et al., N-(cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio-2-thiazolyl]-4-piperidinecarboxamide(BMS-387032), a Highly Efficacious and Selective Antitumor Agent, J. Med. Chem., 47, 1719-1728 (2004).
81. X Zhang, J Schwartz, X Guo, S Bhatia, E Cao, L Chen, Z Zhang, M Edidin, S Nathenson, S Almo, Structural and Functional Analysis of the Costimulatory Receptor Programmed Death-1, Immunity, 20, 337-347 (2004).[ premier ]
82. T Sakmar, Rhodopsin, Encyclopedia of Neuroscience, p. 3, Elsevier Science B.V., Amsterdam (2004).
83. T Bartfai, J Benovic, J Bockaert, R Bond, M Bouvier, A Christopoulos, O Civelli, L Devi, S George, et al., Twenty Questions: The State of GPCR Research in 2004, Nat. Rev. Drug Discov., 3, 575-626 (2004).[ premier ]
84. W Barton, J Himanen, A Antipenko, D Nikolov, Structures of Axon Guidance Molecules and their Neuronal Receptors, Adv. Protein Chem., 68, 65-106 (2004).
85. T Sakmar, Twenty Years of the Magnificent Seven, The Scientist, 19, 22-23 (2004).
86. C Seibert, T Sakmar, Small-Molecular Antagonists of CCR5 and CXCR4: A Promising New Class of Anti-HIV-1 Drugs, Curr. Pharm. Design, 10, 2041-2062 (2004).
87. D Nesic, Y Hsu, E Stebbins, Assembly and Function of a Bacterial Genotoxin, Nature, 429, 429-433 (2004).[ premier ]
88. F Smith, C Vearing, M Lackmann, H Treutlein, J Himanen, K Chen, A Saul, D Nikolov, A Boyd, Dissecting the EphA3/ephrin-A5 Interactions Using a Novel Functional Mutagenesis Screen , J. Biol. Chem., 279, 9522-9531 (2004).
89. W Shi, L Ting, G Kicska, A Lewandowicz, P Tyler, G Evans, R Furneaux, K Kim, S Almo, V Schramm, Plasmodium Falciparum Purine Nucleoside Phosphorylase: Crystal Structures, Immucillin Inhibitors, and Dual Catalytic Function, J. Biol. Chem., 279, 18103 (2004).
90. M Vetting, S Magnet, E Nieves, S Roderick, J Blanchard, A Bacterial Acetyltransferase Capable of Regioselective N-acetylation of Antibiotics and Histones, Chem. Bio., 11(4), 565-73 (2004).[ premier ]
91. L Bickford, E Mossessova, J Goldberg, A Structural View of the VOPII Vesicle Coat, Curr. Opin. Struct. Biol., 14, 147-153 (2004).[ premier ]
92. E Billick, C Seibert, P Pugach, T Ketas, A Trkola, M Endres, N Murgolo, E Coates, G Reyes, et al., The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry is Explained by a Single Amino Acid Difference and Suggests a Mechanism of Action for these Inhibitors, J. Virology, 78, 4134-4144 (2004).
93. D Pilloff, K Dabovic, M Romanowski, J Bonanno, M Doherty, S Burley, T Lehy, The Kinetic Mechanism of Phosphomevalonate Kinase, J. Biol. Chem., 278, 4510-4514 (2003). [ ]
94. W Barton, B Liu, D Tzvetkova, P Jeffreey, A Fournier, D Sah, R Cate, S Strittmatter, D Nikolov, Structure and Axon Outgrowth Inhibitor Binding of the Nogo-66 Receptor and Related Proteins, EMBO J., 22, 3291-3302 (2003).[ premier ]
95. J Sun, A Fedorov, S Lee, X Guo, K Shen, D Lawrence, S Almo, Z Zhang, Crystal Structure of PTP1B Complexed with a Potent and Selective Bidentate Inhibitor, J. Biol. Chem., 278, 12406-12414 (2003).
96. J Sun, L Wu, A Fedorov, S Almo, Z Zhang, Crystal Structure of the Yersinia Protein-Tyrosine Phosphatase YopH Complexed with a Specific Small Molecule Inhibitor, J. Biol. Chem., 278, 33392-33399 (2003).
97. F Burling, R Kniewel, J Buglino, T Chadha, A Beckwith, C Lima, Structure of Escherichia Coli Uridine Phosphorylase at 2.0 Angstrom, Acta Cryst. D, 59, 73-76 (2003). [ ]
98. W Shi, D Ostrov, S Gerchman, H Kycia, W Studier, W Edstrom, A Bresnick, J Ehrlich, J Blanchard, et al, High-Throughput Structural Biology & Proteomics, Protein Arrays, Biochips & Proteomics: The Next Phase of Genomics Discovery, p. 299-324, Marcel Dekker, New York (2003). [ ]
99. K Kamada, R Roeder, S Burley, Molecular Mechanism of Recruitment of TFIIF - Associating RNA Polymerase C-Terminal Domain Phosphatase (FCP1) by Transcription Factor IIF, Proc Natl Acad Sci USA, 100(5), 2296-2299 (2003). [ ][ premier ]
100. X Zhang, J Schwartz, S Almo, S Nathenson, Crystal Structure of the Receptor-Binding Domain of Human B7-2: Insights into Organization and Signaling, Proc Natl Acad Sci USA, 100(5), 2586-2591 (2003). [ ][ premier ]
101. S Vorobiev, B Strokopytov, D Drubin, C Frieden, S Ono, J Condeelis, P Rubenstein, S Almo, The Structure of Non-Vertebrate Actin: Implications for the ATP Hydrolytic Mechanism, Proc Natl Acad Sci USA, 100(10), 5760-5765 (2003). [ ][ premier ]
102. E Mossessova, L Bickford, J Goldberg, SNARE Selectivity of the COPII Coat, Cell, 114, 483-495 (2003). [ ][ premier ]
103. S Nair, S Burley, X-ray Structures of Myc-Max and Mad-Max Recognizing DNA: Molecular Bases of Regulation by Proto-Oncogenic Transcription Factors, Cell, 112, 193-205 (2003).[ premier ]
104. T Schwartz, G Blobel, Structural Basis for the Function of the beta Subunit of the Eukaryotic Signal Recognition Particle Receptor, Cell, 112(6), 793-803 (2003). [ ][ premier ]
105. M Perbandt, E Guthohrlein, W Rypniewski, K Idakieva, S Stoeva, W Voelter, N Genov, C Betzel, The Structure of a Functional Unit from the Wall of a Gastropod Hemocyanin Offers a Possible Mechanism for Cooperativity, Biochemistry, 42, 6341-6346 (2003). [ ]
106. A Lewandowicz, W Shi, G Evans, P Tyler, R Furneaux, L Basso, D Santos, S Almo, V Schramm, Over-the-Barrier Transition State Analogues and Crystal Structure with Mycobacterium Tuberculosis Purine Nucleoside Phosphorylase, Biochemistry, 42, 6057-6066 (2003). [ ]
107. G Wu, G Xu, B Schulman, P Jeffrey, J Harper, N Pavletich, Structure of a Beta-TrCPI-Skp1-Beta-Catenin Complex: Destruction Motif Binding and Lysine Specificity of the SCF(beta-TrCP1) Ubiquitin Ligase, Mol. Cell, 6, 1445-1456 (2003).[ premier ]
108. K Kamada, F Hanoaka, S Burley, Crystal Structure of the MazE/MazF Complex: Molecular Bases of Antidote-Toxin Recognition, Mol. Cell, 11, 875-884 (2003). [ ][ premier ]
109. C Fabrega, S Shuman, C Lima, Structure of Candida Albicans mRNA Guanylytransferase Bound to Phosphorylated CTD of RNA Polymerase II, Mol. Cell, 11, 1549-1561 (2003).[ premier ]
110. E Campbell, J Tupy, T Gruber, S Wang, M Sharp, C Gross, S Darst, Crystal Structure of Escherichia Coli E with the Cytoplasmic Domain of its anti-RseA, Mol. Cell, 11, 1067-078 (2003).[ premier ]
111. M Lilic, V Galkin, A Orlova, M VanLoock, E Egelman, C Stebbins, Salmonella SipA Polymerizes Actin by Stapling Filaments with Nonglobular Protein Arms, Science, 301, 1918-1921 (2003).[ premier ]
112. E Stravridi, K Harris, Y Huyen, J Bothos, P Verwoerd, S Stayrook, N Pavletich, P Jeffrey, F Luca, Crystal Structure of a Human Mob1 Protein: Toward Understanding Mob-Regulated Cell Cycle Pathways, Structure, 11, 1163-1170 (2003).
113. S Ray, J Bonanno, H Chen, S Wu, H De Lencastre, A Tomasz, S Burley, Crystal Structure of a Methanococcus Jannaschii DNA-Binding Protein: Implications for Antibiotic Resistance in Staphyloccoccus Aureus, Proteins: Struc. Func. Genet., 50, 170-173 (2003).
114. A Gogos, H Mu, F Bahna, C Gomez, L Shapiro, Crystal Structure of YdcE Protein from Bacillus Subtilis, Proteins: Struc. Func. Genet., 53, 320-322 (2003).
115. A Padyana, S Burley, Crystal Structure of Shikimate 5-Dehydrogenase (SDH) Bound to NADP: Insights into Function and Evolution, Structure, 11, 1005-1013 (2003).
116. A Antipenko, J Himanen, K Van Leyen, V Nardi-Dei, J Lesniak, W Barton, K Rajashankar, M Lu, C Hoemme, et al., Structure of the Semaphorin-3A Receptor-Binding Module, Neuron, 39, 589-598 (2003).[ premier ]
117. X Zhang, J Schwartz, S Almo, S Nathenson, Expression, Refolding, Purification, Molecular Characterization, Crystallization and Preliminary X-Ray Analysis of the Receptor Binding Domain of Human B7-2, Protein Expr. Purif., 25, 105-113 (2003).
118. A Larsson, R Andersson, J Stahlberg, L Kenne, T Jones, Dextranase from Penicillium minioluteum: Reactin Course, Crystal Structure, and Product Complex, Structure, 11, 1111-1121 (2003). [ ]
119. C Albermann, A Soriano, J Jiang, H Vollmer, J Biggins, W Barton, J Lesniak, D Nikolov, J Thorson, Substrate Specificity of NovM: Implications for Novobiocin Biosynthesis and Glycorandomization, Org. Lett., 5, 933-936 (2003). [ ]
120. J Coyle, D Nikolov, GABARAP: Lessons for Synaptogenesis, The Neuroscientist, 9, 205-216 (2003).
121. J Himanen, D Nikolov, In Focus: Eph Receptors and Ephrins, Int. J. Biochem. Cell Biol., 35, 130-134 (2003). [ ]
122. J Himanen, D Nikolov, Eph Receptors and Ephrins a Structural View, Trends Neurosci., 26, 46-51 (2003).[ premier ]
123. R Kniewel, J Buglino, V Shen, T Chadna, A Beckwith, C Lima, Structural Analysis of Saccharomyces Cerevisiae Myo-Inositol Phosphate Synthase, J. Struct. Funct. Genomics, 3, 129-134 (2002). [ ]
124. S Burley, J Bonanno, Structuring the Universe of Proteins, Annu. Rev. Genom.Hum. G., 3, 243-262 (2002).[ premier ]
125. E Stavridi, Y Huyen, I Loreto, D Scolnick, T Halazonetis, N Pavletich, P Jeffrey, Crystal Structure of the FHA Domain of the Chfr Mitotic Checkpoint Protein and Its Complex with Tungstate., Structure, 10(7), 891-9 (2002).
126. G Gainsford, Crystals Great And Small, Chem. In New Zealand, 66(2), 29-32 (2002).
127. M Chance, A Bresnick, S Burley, J Jiang, C Lima, A Sali, S Almo, J Bonanno, J Buglino, et al., Structural Genomics: A Pipeline for Providing Structures for the Biologist, Protein Sci., 11, 723-738 (2002).
128. J Schwartz, X Zhang, S Nathenson, S Almo, Structural Mechanisms of Co-Stimulation, Nat. Immunol., 5, 427-434 (2002).[ premier ]
129. J Coyle, S Qamar, K Rajashankar, D Nikolov, Structure of GABARAP in Two Conformations: Implications for GABA(A) Receptor Localization and Tubulin Binding, Neuron, 33, 63-74 (2002).[ premier ]
130. M Romanowski, J Bonanno, S Burley, Crystal Structure of the Streptococcus Pneumoniae Phosphomevalonate Kinase, a Member of the GHMP Kinase Superfamily, Proteins: Struc. Func. Genet., 47( 4), 568-571 (2002).
131. M Romanowski, S Burley, Crystal Structure of the Escherichia Coli Shikimate Kinase I (AroK) that Confers Sensitivity to Mecillinam, Proteins: Struc. Func. Genet., 47( 4), 558-562 (2002).
132. M Romanowski, J Bonanno, S Burley, Crystal Structure of the Escherichia coli Glucose-Inhibited Division ProteinB(GidB) Reveals a Methyltransferase Fold, Proteins: Struc. Func. Genet., 47, 563–567 (2002).
133. M Romanowski, S Gibney, S Burley, Crystal Structure of the Escherichia coli SbmC Protein That Protects Cells From the DNA Replication Inhibitor Microcin B17, Proteins: Struc. Func. Genet., 47, 403–407 (2002).
134. A Deaconescu, A Roll-Mecak, S Gerchman, H Kycia, F Studier, J Bonanno, S Burley, X-Ray Structure of Saccharomyces Cerevisiae Homologous Mitochondrial Matrix Factor 1 (Hmf1), Proteins: Struc. Func. Genet., 48, 431-436 (2002).
135. H Yang, P Jeffrey, J Miller, E Kinnucan, Y Sun, N Thoma, N Zheng, P Chen, N Zheng, et al, BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure, Science, 297, 1837-1848 (2002).[ premier ]
136. S Roderick, W Chan, D Agate, L Olsen, M Vetting, K Rajashankar, D Cohen, Structure of human phosphatidylcholine transfer protein in complex with its ligand, Nat. Struct. Mol. Biol., 9, 507-511 (2002).[ premier ]
137. E Campbell, O Muzzin, M Chlenov, J Sun, C Olson, O Weinman, M Trester-Zedlitz, S Darst, Structure of the Bacterial RNA Polymerase Promoter Specificity Sigma Subunit, Mol. Cell, 9, 527-539 (2002).[ premier ]
138. C Groft, S Burley, Recognition of eIF4G by Rotavirus NSP3 Reveals a Basis for mRNA Circularization, Mol. Cell, 6, 1273-1283 (2002).[ premier ]
139. G Kicska, P Tyler, G Evans, R Furneaux, W Shi, A Fedorov, A Lewandowicz, S Cahill, S Almo, V Schramm, Atomic Dissection of the Hydrogen Bond Network for Transition-State Analogue Binding to Purine Nucleoside Phosphorylase, Biochemistry, 41, 14489-14498 (2002). [ ]
140. C Kielkopf, S Burley, X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition, Biochemistry, 41, 11711-11720 (2002).
141. E Wolf, J De Angelis, E Khalil, P Cole, S Burley, X-Ray Crystallographic Studies of Serotonin N-Acetyltransferase Catalysis and Inhibition, J. Mol. Biol., 317, 215-224 (2002).
142. R Deo, C Groft, K Rajashankar, S Burley, Recognition of the Rotavirus mRNA 3' Consensus by an Asymmetric NSP3 Homodimer, Cell, 108, 71-81 (2002).[ premier ]
143. J Himanen, D Nikolov, Purification, Crystallization and Preliminary Characterization of the EphB2-ephrinB2 Complex, Acta Cryst. D, D58, 533-535 (2002).
144. M Romanowski, R Soccio, J Breslow, S Burley, Crystal Structure of the Mus Musculus Cholesterol-regulated START Protein 4 (StarD4) Containing a StAR-related Lipid Transfer Domain, Proc Natl Acad Sci USA, 99(10), 6949-6954 (2002).[ premier ]
145. R Soccio, R Adams, M Romanowski, E Sehayek, S Burley, J Breslow, The Novel Cholesterol-Regulated StarD4 Gene Encodes a StAR-Related Lipid Transfer Protein with two Closely Related Homologues, Proc Natl Acad Sci USA, 99, 6943-6948 (2002). [ ][ premier ]
146. W Barton, J Biggins, J Jiang, J Thorson, D Nikolov, Expanding Pyrimidine Diphosphosugar Libraries via Structure-based Nucleotidylyltransferase Engineering, Proc Natl Acad Sci USA, 99(21), 13397-13402 (2002).[ premier ]
147. W Chan, S Roderick, D Cohen, Human Phosphatidylcholine Transfer Protein: Purification, Crystallization and Preliminary X-ray Diffraction, Biochim Biophys Acta, 1596( 1), 1-5 (2002).
148. S Burley, J Bonanno, Structural Genomics, Structural Bioinformatics, p. 591-612, Academic Press, New York (2002). [ ]
149. J Dewan, A Feeling-Taylor, Y Puius, L Patskovska, Y Patskovsky, R Nagel, S Almo, R Hirsch, Structure of Mutant Human Carbonmonoxyhemoglobin C (betaE6K) at 2.0 A Resolution, Acta Cryst. D, 58, 2038-2042 (2002).
150. Y Tseng, B Schafer, S Almo, D Wirtz, Functional Synergy of Actin Filament Cross-Linking Proteins, J. Biol. Chem., 277, 25609-25616 (2002).
151. M Bubb, L Govindasamy, E Yarmola, S Vorobiev, S Almo, T Somasundaram, M Chapman, M Agbandje-McKenna, R McKenna, Polylysine Induces an Antiparallel Actin Dimer that Nucleates Filament Assembly: Crystal Structure at 3.5-A Resolution, J. Biol. Chem., 277, 20999-21006 (2002).
152. D Ostrov, M Roden, W Shi, E Palmieri, G Christianson, L Mendoza, G Villaflor, D Tilley, N Shastri, et al., How H13 Histocompatibility Peptides Differing by a Single Methyl Group and Lacking Conventional MHC Binding Anchor Motifs Determine Self-Nonself Discrimination, J. Immunol., 1, 283-289 (2002).[ premier ]
153. J Lesniak, W Barton, D Nikolov, Structural and Functional Characterization of the Pseudomonas Hydroperoxide Resistance Protein Ohr, EMBO J., 21(24), 6649-6659 (2002).[ premier ]
154. L Wang, C Lima, S Shuman, Structure and Mechanism of T4 Polynucleotide Kinase: an RNA Repair Enzyme, EMBO J., 21(14), 3873-3880 (2002).[ premier ]
155. W Joo, P Jeffrey, S Cantor, M Finnin, D Livingston, N Pavletich, Structure of the 53BP1 BRCT Region Bound to p53 and its Comparison to the Brcal BRCT Structure, Genes Dev., 16, 583-593 (2002). [ ][ premier ]
156. A Niedzwiecka, J Marcotrigiano, J Stepinski, M Jankowska-Anyszka, A Wyslouch-Cieszynska, M Dadlez, A Gingras, P Mak, E Darzynkiewicz, et al., Biophysical studies of eIF4E Cap-Binding Protein: Recognition of mRNA 5' Cap Structure and Synthetic Fragments of eIF4G and 4E-BP1 Proteins, J. Mol. Biol., 319, 615-635 (2002).
157. A Bobkov, A Muhlrad, K Kokabi, S Vorobiev, S Almo, E Reisler, Structural Effects of Cofilin on Longitudinal Contacts in F-Actin, J. Mol. Biol., 323, 739-750 (2002).
158. K Schneibner, J DeAngelis, S Burley, P Cole, Investigation of the Roles of Catalytic Residues in Serotonin N-Acetyltransferase, J. Biol. Chem., 277, 18118-18126 (2002). [ ]
159. B Shin, D Maag, A Roll-Mecak, M Arefin, S Burley, J Lorsch, T Dever, Uncoupling of Initiation Factor eIF5B/IF2 GTPase and Translational Activities by Mutations that Lower Ribosome Affinity, Cell, 111, 1015-1025 (2002). [ ][ premier ]
160. S Burley, K Kamada, Transcription Factor Complexes, Curr. Opin. Struct. Biol., 12, 225-230 (2002).[ premier ]
161. J Bonanno, S Burley, Structural Genomics of Proteins Contributing to Conserved Biochemical Pathways/Processes, Curr. Opin. Struct. Biol., 12, 383-391 (2002).[ premier ]
162. Y Tseng, E Fedorov, J McCaffery, S Almo, D Wirtz, Micromechanics and Ultrastructure of Actin Filament Networks Crosslinked by Human Fascin: A Comparison with Alpha-Actinin, J. Mol. Biol., 2, 351-366 (2001).
163. D Klein, T Schmeing, P Moore, T Steitz, The Kink-Turn: A New RNA Secondary Structure Motif, EMBO J., 20, 4214-4221 (2001).[ premier ]
164. K Kamada, F Shu, H Chen, S Malik, G Stelzer, R Roeder, M Meisterernst, S Burley, Crystal Structure of Negatiave Cofactor 2 Recognizing the TBP-DNA Transcription Complex, Cell, 106, 71-81 (2001).[ premier ]
165. R Deo, N Sonenberg, S Burley, X-Ray Structure of the Human Hyperplastic Discs Protein: An Ortholog of the C-Terminal Domain of Poly(A) Binding Protein, Proc Natl Acad Sci USA, 98, 4414-4419 (2001).[ premier ]
166. J Bonanno, C Edo, N Eswar, U Pieper, M Romanowski, V Ilyin, S Gerchman, H Kycia, W Studier, et al., Structural Genomics of Enzymes Involved in Sterol/Isoprenoid Biosynthesis, Proc Natl Acad Sci USA, 98, 12896-12901 (2001).[ premier ]
167. J Himanen, K Rajashankar, M Lackmann, C Cowan, M Henkemeyer, D Nikolov, Crystal Structure of an Eph Receptor-ephrin Complex, Nature, 414, 933-938 (2001).[ premier ]
168. J Schwartz, X Zhang, A Fedorov, S Nathenson, S Almo, Structural Basis for Costimulation by the Human CTLA-4/B7-2 Complex, Nature, 410, 604-608 (2001).[ premier ]
169. J Walker, R Corpina, J Goldberg, Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair., Nature, 412, 607-614 (2001).[ premier ]
170. X Zhang, J Schwartz, S Nathenson, S Almo, Crystallization and Preliminary X-Ray Analysis of the Complex Between Human CTLA-4 and B7-2, Acta Cryst. D, 57, 898-899 (2001).
171. W Barton, J Lesniak, J Biggins, P Jeffrey, J Jiang, K Rajashankar, J Thorson, D Nikolov, Structure, Mechanism and Engineering of a Nucleotidylytransferase as a First Step Toward Glycorandomization, Nat. Struct. Mol. Biol., 8, 545-551 (2001).[ premier ]
172. M Finnin, J Donigian, N Pavletich, Structure of the Histone Deacetylase SIRT2, Nat. Struct. Mol. Biol., 20018, 621-625 (2001).[ premier ]
173. W Shi, K Tanaka, T Crother, M Taylor, S Almo, V Schramm, Structural Analysis of Adenine Phosphoribosyltransferase from Saccharomyces Cerevisiae, Biochemistry, 36, 10800-10809 (2001).
174. A Roll-Mecak, B Shin, T Dever, S Burley, Engaging the Ribosome: Universal IFs of Translation, Trends Biochem. Sci., 26, 705-709 (2001).[ premier ]
175. C Ralston, B Sclavi, M Sullivan, M Deras, S Woodson, M Chance, M Brenowitz, Time-Resolved Synchrotron X-Ray Footprinting and its Application to RNA Folding, Meth. Enzymol., 317, 353-368 (2000).
176. S Burley, An Overview of Structural Genomics, Nat. Struct. Mol. Biol., 7, 932-934 (2000).[ premier ]
177. C Groft, R Beckmann, A Sali, S Burley, Crystal Structure of Ribosome Anti-Association Factor eIF6, Nat. Struct. Mol. Biol., 7, 1156-1164 (2000).[ premier ]
178. O Kleifeld, A Frenkel, O Bogin, M Eisenstein, V Brumfeld, Y Burstein, I Sagi, Inhibition Studies of Alcohol Dehydrogenase from Thermoanaerobacter Brockii: Porposed Structure for the Catalytic Intermediate State, Biochemistry, 39, 7702-7711 (2000).
179. S Silverman, M Deras, S Woodson, S Scaringe, T Cech, Multiple folding pathways for the P4-P6 RNA domain, Biochemistry, 39, 12465-12475 (2000).
180. A Roll-Mecak, C Cao, T Dever, S Burley, X-Ray Structures of the Universal Translation Initiation Factor IF2/elF5B: Conformational Changes on GDP and GTP Binding, Cell, 103, 781-792 (2000).[ premier ]
181. i Sagi, Y Hochman, G Bunker, S Carmeli, C Carmeli, The penta-coordinated vanadium formed on binding of ADP-vanadate-Mg(II) to CF1-ATPase functions as a transition-state inhibitor, J. Synch. Rad., 6, 409-410 (1999).
182. L Powers, M Griep, Escherichia Coli Primase Zinc is Sensitive to Substrate and Cofactor Binding, Biochemistry, 38(23), 7413-7420 (1999).

[ premier ] - A publication is considered premier if the journal has an impact factor of 6 or greater (from Journal Citation Report 2003, Thomson Institute for Scientific Information). These journals represent approximately the top 3% of all journals. Two additional journals are included in the NSLS premier list, Applied Physics Letters (impact factor 4.0) and Environmental Sciences and Technology (impact factor 3.6), because these journals represent the "best in class" for the NSLS industrial and environmental science users, even though their impact factors are less than 6.