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May 21, 2007 2007 Joint NSLS/CFN Users’ Meeting WorkshopNanomedicine: Diagnostics and TreatmentAs part of the 2007 Joint NSLS/CFN Users’ Meeting, a Nanomedicine II Workshop, organized by Stony Brook University professors Perena Gouma and Molly Frame, was held on May 22. Nanomedicine is the medical diagnosis, monitoring, and treatment at the level of single molecules or molecular assemblies that provide structure, control, signaling, homeostasis, and mobility in cells. It is a very important research direction in order to understand the cellular mechanisms in living cells and to develop advanced technologies for early diagnosis and treatment of various diseases. The workshop featured four invited speakers: Dr. Chiming Wei, from Johns Hopkins University; Dr. Omid Farokhzad, from Harvard Medical School; Professor Michael Sheetz, from Columbia University; and Professor Brian Helmke, University of Virginia.
Dr. Wei is the founder of the journal Nanomedicine and of the American Association of Nanomedicine. He presented an overview of the research activities that fall under the umbrella of nanomedicine, such as quantum-dot-based biosensors, cell factories, and nanopump development. With an emphasis to personalized medicine, novel diagnostic tools and therapeutic agents were mostly reviewed in Dr. Wei’s talk. Dr. Farokhzad, representing Prof. Robert Langer’s research at MIT, also focused his talk on targeted therapeutic agents, such as nanostructured drug delivery vehicles for in-vivo tumor reduction studies. The second part of the symposium addressed the interactions of cells with substrates. Dr. Sheetz, as the Director of a Nanomedicine Center funded by the National Institutes of Health, presented a nanomedicine approach to cellular mechanics, such as how substrate rigidity may control cell differentiation. His research explores how cells transform physical force to a biochemical signal; what’s the signaling in response to stretching the cell. Similarly, Dr. Helmke discussed how designing active mechanical cues on substrates affects cell growth, proliferation and differentiation. FOR MORE INFORMATION: |
The National Synchrotron Light Source at Brookhaven National Laboratory in New York, is a national user research
facility funded by the U.S. Department of Energy's Office of Basic Energy Science. The NSLS operates two electron
storage rings: an X-Ray ring and a Vacuum UltraViolet (VUV) ring which provide intense light spanning the electromagnetic
spectrum from the infrared through x-rays. Each year over 2300 scientists from universities, industries and government
labs perform research at the NSLS.
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