Life Science

Structure of TonB in Complex with FhuA, E. Coli Outer Membrane Receptor

P.D. Pawelek, N. Croteau, C. Ng-Thow-Hing, C.M. Khursigara, N. Moiseeva, M. Allaire, and J.W. Coulton

A New Folding Paradigm for Repeat Proteins

T. Kajander, A.L. Cortajarena, E.R.G. Main, S.G.J. Mochrie, and L. Regan

Structural Basis for Gene Regulation by a Thiamine Pyrophosphate-Sensing Riboswitch

A. Serganov, A. Polonskaia, A. Tuân Phan, R.R. Breaker, and D.J. Patel

Structural Insight into Antibiotic Fosfomycin Biosynthesis by a Mononuclear Iron Enzyme

L.J. Higgins, F. Yan, P. Liu, H.-W. Liu, and C.L. Drennan

Co-Localization of -Amyloid Deposits and Metal Accumulation in Alzheimer’s Disease

Q. Wang, T.P. Telivala, R.J. Smith, A. Lanzirotti, J. Miklossy, and L.M. Miller

Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum

N.H. Tolia, E.J. Enemark, B. Kim Lee Sim, and L. Joshua-Tor

Disulfide Trapped Structure of a Repair Enzyme Interrogating Undamaged DNA Sheds Light on Damaged DNA Recognition

A. Banerjee, W. Santos, and G.L. Verdine

A Redox Reaction in Axon Guidance: Structure and Enzymatic Activity of MICAL

M. Nadella, M.A. Bianchet, S.B. Gabelli, and L.M. Amzel

Crystal Structures of Catalytic Complexes of the Oxidative DNA/RNA Repair Enzyme AlkB

B. Yu, W.C. Edstrom, J. Benach, Y. Hamuro, P.C. Weber, B.R. Gibney, and J.F. Hunt

Crystal Structure of Human Arginase I at 1.29 Å Resolution and Exploration of Inhibition in the Immune Response

L. Di Costanzo, G. Sabio, A. Mora, P.C. Rodriguez, A.C. Ochoa, F. Centeno, and D.W. Christianson

Mechanism of Activation for Transcription Factor PhoB Suggested by Different Modes of Dimerization in the Inactive and Active States

P. Bachawat, G.V.T. Swapna, G.T. Montelione, and A.M. Stock

RNA Silencing Suppressor p21 Adopts an Unusual siRNA-Binding Octameric Ring Architecture

K. Ye and D.J. Patel

Mechanism of DNA Translocation in a Replicative Hexameric Helicase

E.J. Enemark and L. Joshua-Tor