Marc Allaire is a member of the NIGMS East Coast Structural Biology Facility which operates beamline X6A for macromolecular crystallography. This facility serves expert and non-expert crystallographer to address structural biology questions. The mission is to help a growing community of life scientists to explore all aspects of macromolecular crystallography. Marc Allaire's research focuses on the application of synchrotron-based techniques for chemical genetics and to study the structure and function of proteins.. Professional Activities

Education:

• Ph.D. 1992: Biochemistry, University of Sherbrooke
• M.A. 1985: Biochemistry, University of Sherbrooke

Key Publications:

• P Pawelek, N Croteau, C Ng-Thow-Hing, C Khursigara, N Moiseeva, M Allaire, J Coulton, Structure of TonB in Complex with FhuA, E. Coli Outer Membrane Receptor, Science, 312, 1399-1402 (2006).
• J Sygusch, M Allaire, Sequential radiation damage in protein crystallography, Acta Cryst. A, 44, 443-448 (1988).
• M Allaire, Structure tridimensionnelle de l'aldolase de muscle de lapin à une résolution de 2.1A, Ph.D. Thesis. Université de Sherbrooke, Sherbrooke (1992).
• M Allaire, M Chernaia, B Malcolm, M James, Picornaviral 3C cysteine proteinases have a fold similar to the chymotrypsin-like serine proteinases, Nature, 369, 72-76 (1994).
• M Allaire, Y Li, R MacKenzie, M Cygler, The 3-D Structure of a folate-dependent dehydrogenase / cyclohydrolase bifunctional enzyme at 1.5A resolution, Structure, 6, 173-182 (1998).

All Publications

Links:

• Beamline X6A - NIGMS East Coast Structural Biology Facility